Optimization of prevention of infectious complications during prostate biopsy

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Abstract

Prostate cancer (PCa) is one of the most common malignant neoplasms in middle-aged and elderly men. Transrectal ultrasound guided prostate biopsy is the standard method for diagnosing prostate cancer but is associated with a high incidence of infectious compli-cations.

A review of the literature on optimizing the prevention of infectious complications when performing transrectal prostate biopsy is presented. The main risk factors and the common measures to prevent the development of complications are discussed, including a study of using fosfomycin trometamol as the preferred drug for antibacterial prophylaxis. Fosfomycin meets the requirements for empirical prophylaxis, but further clinical studies are needed.

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About the authors

K. B. Kolontarev

Moscow Urological Center of S.P. Botkin City Clinical Hospital; Institute of the Clinical Medicine named after N.A. Semashko FGBOU VO «Russian University of Medicine»

Email: kb80@yandex.ru

Ph.D., MD, Deputy Chief, professor at the Department of Urology

Russian Federation, Moscow; Moscow

R. V. Stroganov

Moscow Urological Center of S.P. Botkin City Clinical Hospital

Email: r.v.stroganov@gmail.com

Ph.D., assistant at the Department of Urology

Russian Federation, Moscow

D. Yu. Pushkar

Moscow Urological Center of S.P. Botkin City Clinical Hospital; Institute of the Clinical Medicine named after N.A. Semashko FGBOU VO «Russian University of Medicine»

Author for correspondence.
Email: pushkardm@mail.ru

Academician of RAS, Ph.D., MD, Professor, Chief, Head of the Department of Urology

Russian Federation, Moscow; Moscow

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