Analysis of the prevalence of nonspecific urinary tract infection in patients with tuberculosis among residents of the Bukhara region of the republic of Uzbekistan

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Aim. To analyze the prevalence of nonspecific UTI in patients with tuberculosis and to evaluate the efficiency of therapy and prevention measures.

Material and methods. A total of 936 patients with tuberculosis of various localizations aged from 18 to 96 years were examined. There were 447 men (47.8%) and 489 women (52.2%). A diagnosis of nonspecific UTI was done using following criteria: the presence of characteristic symptoms, leukocyturia and bacteriuria detected by microscopic examination of the urine sediment, positive urine culture for nonspecific species, negative urine tests for Mycobacterium tuberculosis.

Results. The prevalence of nonspecific UTI among 936 patients with tuberculosis was 18.6% (n=174). Non-specific species were determined in all forms of tuberculosis, but most often in urogenital tuberculosis (74.1%). Proposed therapeutic and prophylactic tactics included antibacterial therapy, herbal drug Kanefron N and sanitary measures. The efficiency of treatment was 94.6%. It should be noted that patients received anti-tuberculosis therapy, and there were no adverse reactions associated with a combination of drugs.

Conclusion. When choosing treatment tactics, it is necessary to take into account the presence of structural and functional changes in the urinary tract, which reduce treatment efficiency.

Full Text

Restricted Access

About the authors

Z. R. Rashidov

Tashkent Pediatric Medical Institute of the Ministry of Health of the Ministry of Health of the Republic of Uzbekistan

Author for correspondence.
Email: dr-zrr@mail.ru

Ph.D., MD, associate professor at the Department of Surgical Disease of Tashkent Pediatric Medical Institute of the Ministry of Health of the Ministry of Health of the Republic of Uzbekistan

Uzbekistan, Tashkent

S. I. Azimov

Course of urology of faculty and hospital surgery of the Bukhara State Medical Institute of the Ministry of Health of the Republic of Uzbekistan

Email: sardorbekazimov87@gmail.com

assistant of the course of urology of faculty and hospital surgery of the Bukhara State Medical Institute of the Ministry of Health of the Republic of Uzbekistan

Uzbekistan, Bukhara

References

  1. Uijen A.A., van de Lisdonk E.H. Multimorbidity in primary care: prevalence and trend over the last 20 years. Eur J Gen Pract. 2008,14(Suppl 1):28–32.
  2. Van den Akker M., Buntinx F., Metsemakers J.F., et al. Multimorbidity in general practice: prevalence, incidence, and determinants of co-occurring chronic and recurrent diseases. J Clin Epidemiol. 1998;51(5):367–375.
  3. Britt H.C., Harrison C.M., Miller G.C., Knox S.A. Prevalence and patterns of multimorbidity in Australia. Med J Aust. 2008;189(2):72–77.
  4. Fortin M., Stewart M., Poitras M.E., et al. A systematic review of prevalence studies on multimorbidity: toward a more uniform methodology. Ann Fam Med. 2012;10(2):142–151.
  5. Lawn S.D., Zumla A.I. Tuberculosis. Lancet. 2011;378(9785):57–72.
  6. Aminev H.K., Sharipov R.A., Azamatova M.M., Aminev E.H., Davydova N.A. Tuberculosis and concomitant diseases. An information letter for doctors. Ufa, 2017 20 p. Russian (Аминев Х.К., Шарипов Р.А., Азаматова М.М., Аминев Э.Х., Давыдова Н.А. Туберкулез и сопутствующие заболевания. Информационное письмо для врачей. Уфа, 2017 г. 20 с.).
  7. Seitbaev Y.Sh., Parpieva N.N., Dzhurabayeva M.H. et al. Characteristics of destructive pulmonary tuberculosis in patients with type 2 diabetes mellitus. Tuberculosis and lung diseases. 2015;6:132-133. Russian (Сейтбаев Ы.Ш., Парпиева Н.Н., Джурабаева М.Х. с соавт. Характеристика деструктивного туберкулеза легких у больных сахарным диабетом 2-го типа. Туберкулез и болезни легких. 2015;6:132–133).
  8. Tashpulatova F.K., Mukhtarov D.Z. A method for predicting the risk of adverse reactions in patients with pulmonary tuberculosis caused by a drug-resistant pathogen. Phthisiology and pulmonology. 2016;1(12):22–33. Russian (Ташпулатова Ф.К., Мухтаров Д.З. Метод прогнозирования риска развития побочных реакций у больных туберкулезом легких, вызванных возбудителем с лекарственной устойчивостью. Фтизиатрия и пульмонология. 2016;1(12):22–33).
  9. Zangieva Z.A., Zhuchenko O.G., Grabarnik A.E. The risk of urological diseases in women of reproductive age with tuberculosis. Tuberculosis and lung diseases. 2014;(11):37-41. Russian (Зангиева З.А., Жученко О.Г., Грабарник А.Е. Риск урологических заболеваний у женщин репродуктивного возраста, больных туберкулезом. Туберкулез и болезни легких. 2014;(11):37–41).
  10. Kulchavenya E, Cherednichenko A. Urogenital tuberculosis, the cause of ineffective antibacterial therapy for urinary tract infections. Ther Adv Urol. 2017;10(3):95–101. doi: 10.1177/1756287217745772
  11. Rashidov Z.R., Mukhtarov Sh.T., Azimov S.I. Possibilities of therapeutic and preventive tactics in benign prostatic hyperplasia in tuberculosis patients. Tuberculosis and lung diseases. 2021;7:26-30. Russian (Рашидов З.Р., Мухтаров Ш.Т., Азимов С.И. Возможности лечебно-профилактической тактики при доброкачественной гиперплазии простаты у больных туберкулезом. Туберкулез и болезни легких. 2021;7:26–30).
  12. Rashidov Z.R., Azimov S.I. The Role of the Universal Urological Questionnaire in the Screening of Urological Pathology in Patients with Tuberculosis. American Journal of Medicine and Medical Sciences. 2020;10(10):769–772.
  13. EAU Guidelines. Edn. presented at the EAU Annual Congress Barcelona 2019. ISBN 978-94-92671-04-2
  14. Naber K.G., Perepanova T.S. Review of the efficacy and safety of the drug Kanefron® H. in the treatment and prevention of urogenital and gestational diseases. RMJ. 2012;18:922. Russian (Набер К.Г., Перепанова Т.С. Обзор эффективности и безопасности препарата Канефрон® Н при лечении и профилактике урогенитальных и гестационных заболеваний. РМЖ. 2012;18:922).
  15. Neymark A.I., Suldina A.P., Batanina A.I. The use of Kanefron N in the complex treatment of chronic pyelonephritis. RMJ. 2014;20(6):23–26. Russian (Неймарк А.И., Сульдина А.П., Батанина А.И. Применение препарата Канефрон Н в комплексном лечении хронического пиелонефрита. РМЖ. 2014;20(6):23–26).

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Figure. Structure of nonspecific urinary microflora in tuberculosis patients

Download (127KB)

Copyright (c) 2024 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies