Phytoprophylaxis of complications after extracorporeal lithotripsy

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Abstract

Aim. To evaluate the efficiency of the drug phytolysin (capsules) in the prevention of complications after extracorporeal lithotripsy.

Materials and methods. A total of 15 patients diagnosed with urolithiasis and chronic pyelonephritis in the latent phase were treated. The predominant localization of radiopaque stones no larger than 20 mm in size was the collecting system. The piezoelectric lithotripsy (1-2 sessions) was performed, followed by the administration of the herbal drug Phytolysin in the dosage form of a capsule. The follow-up was carried out after 14- and 30-days using laboratory, ultrasound and x-ray methods.

Results. In the postoperative period, there were no cases of the pyelonephritis, which may result from a short-term disturbance of the upper urinary tract urodynamics due to the passage of stone fragments. The antibacterial, antispasmodic, diuretic and anti-inflammatory effects of Phytolysin ensured positive changes in laboratory and bacteriological tests, contributed to the prevention of postoperative complications after extracorporeal lithotripsy (renal colic, pyelonephritis), and contributed to maintaining renal blood flow within normal limits and significantly reduced the time to stone-free status.

Conclusions. Our results justify the feasibility of using phytolysin in capsules in patients with urolithiasis after extracorporeal lithotripsy. The dosage form in capsules eliminates the undesirable effects associated with the specific smell and taste, that patients noted when using phytolysin in the form of a paste.

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About the authors

M. E. Sitdykova

FGBOU VO Kazan State Medical University of the Ministry of Health of Russia

Author for correspondence.
Email: sitdykova@mail.ru

Ph.D., MD, professor, Head of the Department of Urology named after Academician E.N. Sitdykov, FGBOU VO Kazan State Medical University of the Ministry of Health of Russia

Russian Federation, Kazan

E. A. Zubkov

FGBOU VO Kazan State Medical University of the Ministry of Health of Russia

Email: sitdykova@mail.ru

Ph.D., assistant at the Department of Urology named after Academician E.N. Sitdykov, FGBOU VO Kazan State Medical University of the Ministry of Health of Russia

Russian Federation, Kazan

A. Yu. Zubkov

FGBOU VO Kazan State Medical University of the Ministry of Health of Russia

Email: marina-sitdykova@mail.ru

associate professor at the Department of Urology named after Academician E.N. Sitdykov, FGBOU VO Kazan State Medical University of the Ministry of Health of Russia

Russian Federation, Kazan

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Supplementary files

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2. Fig 1. Frequency of renal colic

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3. Fig. 2. Dynamics of changes in urine tests

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4. Fig 3. Timing of release from VMP stone fragments after DLT (phytolysin)

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