Typical patient models for conservative therapy of male infertility. Pathogenetic approaches and expected effects

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Abstract

Male infertility may be a consequence of various diseases, many of which can be detected during examination. Modern methods of treating male infertility are diverse and include drug and non-drug therapy, diet therapy, and also a combination therapy that combines them, and therefore choosing the optimal approach to each patient is an absolutely important task. We have analyzed the literature on approaches to treating patients with different hormonal status, which allows us to conclude that hormonal therapy in certain cases has a positive effect on spermatogenesis parameters and increases the chance of pregnancy, but at the same time, it is necessary to systematize the available data to identify typical patient models for conservative therapy of male infertility.

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About the authors

Elena A. Epanchintseva

Federal research center of fundamental and translational medicine; LLC «Novosibirsk center of reproductive medicine» GK «Mother and child»; Novosibirsk State Medical University of the Ministry of Health of Russia

Author for correspondence.
Email: epane@yandex.ru
ORCID iD: 0000-0002-9041-2687
SPIN-code: 8560-0588

candidate of medical sciences, senior researcher at the laboratory of endocrinology, assistant professor of the department of urology, endocrinologist-andrologist

 

Russian Federation, 2 Timakova str., Novosibirsk, 630117; 52 Krasny Ave., Novosibirsk, 630091; Kirov str., 29, Novosibirsk, 630037

Vera G. Selyatitskaya

Federal research center of fundamental and translational medicine

Email: ccem@centercem.ru
ORCID iD: 0000-0003-4534-7289
SPIN-code: 9992-0023

doctor of biological sciences, professor, chief researcher of the laboratory of endocrinology

Russian Federation, 2 Timakova str., Novosibirsk, 630117

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