EVALUATION OF RENAL FUNCTION IN PATIENTS WITH SPINAL CORD INJURY


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Abstract

A comprehensive evaluation of renal function in 59 patients with spinal cord injury was performed. Excretory urography, biochemical and ion-selective analysis of serum and daily urine were used. Excretory urography had showed a reduction in the cumulative and excretory renal functions, which was accompanied by an increase in glomerular filtration rate, regardless of the level of damage and the period of traumatic disease. Excretory renal function has undergone a number of changes: 1) decrease in clearance of nitrogenous components; 2) an increase in clearance of mineral components in acute phase; 3) decrease in the rate of calcium excretion. Spinal cord injury contributed to an increase in the stimulating effect of aldosterone on the distal tubules of nephrons function of the kidneys, manifested in the form of increased excretion of potassium in the urine. In case of injury of the cervical and thoracic spine, significant increase in the K/Na coefficient was determined in acute phase, in patients with lumbar spine injury - in the late period.

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About the authors

E. N Shchurova

FSBI «Russian Scientific Center of Restorative Traumatology and Orthopaedics n.a. Academician G.A. Ilizarov» of RMPH

Email: elena.shurova@mail.ru
Leading Researcher at the Laboratory of correction of deformity and lengthening of limbs

M. V Stogov

FSBI «Russian Scientific Center of Restorative Traumatology and Orthopaedics n.a. Academician G.A. Ilizarov» of RMPH

G. V Dyachkova

FSBI «Russian Scientific Center of Restorative Traumatology and Orthopaedics n.a. Academician G.A. Ilizarov» of RMPH

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