Sildenafil citrate dose adjustment for men with erectile dysfunction: personalized approach


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

The high prevalence of erectile dysfunction (ED) in men of all age groups with different psychogenic and organic disorders requires a personalized approach to the choice of treatment. Widely prescribed as first-line treatment for ED, sildenafil can be used in various dosages that are selected depending on comorbidities, tolerability and efficacy of the drug.
Currently there is a wealth of accumulated experience of sildenafil dose adjustment depending on the severity of ED, its etiology and duration, as well as matched to the individual characteristics of copulatory activity. Divisible tablets Tornetis® («Sandoz») give the opportunity to choose an effective and safe dose of sildenafil for of all patients with ED.

Авторлар туралы

I Korneev

Saint-Petersburg First State Medical University n. a. I.P. Pavlov

Saint-Petersburg First State Medical University n. a. I.P. Pavlov

Әдебиет тізімі

  1. Laumann E.O., NicolosiA., GlasserD.B., PaikA., Gingell C., Moreira E., Wang T.; GSSAB Investigators' Group. Sexual problems among women and men aged 40-80 years: prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors. Int. J. Impot. Res. 2005;17:39-57.
  2. Пушкарь Д.Ю., Камалов А.А., Аль-Шукри С.Х. Еркович А.А., Коган М.И., Павлов В.Н., Журавлев В.Н., Берников А.Н. Анализ результатов эпидемиологического исследования распространенности эректильной дисфункции в Российской Федерации. Урология. 2012;6:5-9.
  3. Althof S.E. Quality of life and erectile dysfunction. Urology. 2002;59:803-810.
  4. Goldstein I., Lue T.F., Padma-Nathan H., Rosen R.C., Steers W.D., Wicker P.A.; Sildenafil Study Group. Oral sildenafil in the treatment of erectile dysfunction. 1998. J. Urol. 2002;167:1197-1203. 5.
  5. CappelleriJ.,DuttaguptaS., ShermanN., SiegelR., Crowley A., TsengL., et al. Self-esteem, confidence, and relationships in men with erectile dysfunction treated with sildenafil citrate. J. Gen. Intern. Med. 2004;19(1):209-210.
  6. Hatzimouratidis K., Eardley I., Giuliano F., Hatzichristou D., Moncada I., Salonia A., Vardi Y., Wespes E. Guidelines on Male Sexual Dysfunction: Erectile dysfunction and premature ejaculation. Stockholm, 2014.
  7. Meuleman E., Cuzin B., Opsomer R.J., Hartmann U., Bailey M.J., Maytom M.C., Smith M.D., Osterloh I.H. A dose-escalation study to assess the efficacy and safety of sildenafil citrate in men with erectile dysfunction. BJU Int. 2001;87(1):75-81.
  8. McCullough A.R., Carson C.C., Hatzichristou D. A prospective study of the beneficial effects of dose optimization and customized instructions on patient satisfaction with sildenafil citrate (Viagra) for erectile dysfunction. Urology. 2006;68(3):38-46.
  9. Stuckey B.G., Jadzinsky M.N., Murphy L.J., MontorsiF., Kadioglu A., Fraige F., Manzano P., Deerochanawong C. Sildenafil citrate for treatment of erectile dysfunction in men with type 1 diabetes: results of a randomized controlled trial. Diabetes Care. 2003;26(2):279- 284.
  10. Aversa A., Vitale C., Volterrani M., Fabbri A., Spera G., Fini M., Rosano G.M. Chronic administration of Sildenafil improves markers of endothelial function in men with Type 2 diabetes. Diabet Med. 2008;25(1):37-44.
  11. Schwartz E.J., Wong P., Graydon R.J. Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy. J. Urol. 2004;171:771-774.
  12. Kriston L., Harms A., Berner M.M. A meta-regression analysis of treatment effect modifiers in trials with flexible-dose oral sildenafil for erectile dysfunction in broad-spectrum populations. Int. J. Imp. Res. 2006;18:559-565.
  13. Levinson I.P., Creanga D.L. Appropriate startingbdose of VIAGRA® (sildenafil citrate) for the treatment of erectile dysfunction: pooled analysis of flexible-dose, placebo-controlled, double-blind studies and openlabel extension. J. Sex. Med. 2005;2(1):36.
  14. McCullough A.R., Barada J.H., FawzyA., GuayA.T., HatzichristouD. Achieving treatment optimization with sildenafil citrate (Viagras) in patients with erectile dysfunction. Urology. 2002;60(2B):28-38. 15.
  15. StrobergP.,KaminetskyJ.C.,ParkN.C., GoldfischerE.R., CreangaD.L., Stecher V.J. Hardness, function, emotional well-being, satisfaction and the overall sexual experience in men using 100-mg fixed-dose or flexible-dose sildenafil citrate. Int. J. Imp. Res. 2010;22:284-289.
  16. McCullough A.R., Barada J.H., Fawzy A., Guay A.T., Hatzichristou D. Achieving treatment optimization with sildenafil citrate (Viagra) in patients with erectile dysfunction. Urology. 2002;60:28-38.
  17. Buvat J., Hatzichristou D., Maggi M., Farmer I., Martinez-Jaba- loyas J.M., Miller P.J., Schnetzler G. Efficacy, tolerability and satisfaction with sildenafil citrate 100-mg titration compared with continued 50-mg dose treatment in men with erectile dysfunction. BJU Int. 2008;102(11):1645-1650.
  18. Loran O.B., StrobergP., Lee S.W., ParkN.C., Kim S.W., TsengL.J., Collins S., Stecher V.J. Sildenafil citrate 100 mg starting dose in men with erectile dysfunction in an international, double-blind, placebo- controlled study: effect on the sexual experience and reducing feelings of anxiety about the next intercourse attempt. J. Sex. Med. 2009;6(10):2826-2835.
  19. Gingell C., Sultana S., Hodgson G., Wulff M., Gepi-Attee S. Duration of action of sildenafil citrate in men with erectile dysfunction. J. Sex. Med. 2004;1:179-184.
  20. Levinson I.P. Erectile function is associated with sexual and relationship satisfaction: a pooled analysis of 26 randomized, doubleblind, placebo-controlled trials. J. Sex. Med. 2005;2(1):59.
  21. Montorsi F., Padma-Nathan H., Glina S. Erectile function and assessments of erection hardness correlate positively with measures of emotional well-being, sexual satisfaction, and treatment satisfaction in men with erectile dysfunction treated with sildenafil citrate (Viagra). Urology. 2006;68(3A):26-37.
  22. Levinson I.P., Creanga D.L. Appropriate starting dose of VIAGRAs (sildenafil citrate) for the treatment of erectile dysfunction: pooled analysis of flexible-dose, placebo-controlled, double-blind studies and open-label extension. J. Sex. Med. 2005;2(1):36.

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML
Жүктеу

© Bionika Media, 2015

Осы сайт cookie-файлдарды пайдаланады

Біздің сайтты пайдалануды жалғастыра отырып, сіз сайттың дұрыс жұмыс істеуін қамтамасыз ететін cookie файлдарын өңдеуге келісім бересіз.< / br>< / br>cookie файлдары туралы< / a>