A multicenter variant of renal carcinoma growth
- Authors: Loran ОВ1, Seregin AV1, Tsyganov SE1
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Affiliations:
- Issue: No 5 (2003)
- Pages: 13-15
- Section: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/275024
- ID: 275024
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Abstract
78 kidneys removed for cancer in 1999-2002 were studied for multifocal growth of the tumor. The results demonstrated a direct correlation between multicenter growth of renal cell carcinoma (RCC), size of the primary tumor and stage of the disease. Most of the additional foci were detected at the distance of more than 2.0 cm from the primary tumor, i.e. outside the safety zones in conduction of organ-saving operations. Frequent coincidence of a morphological type of the primary and additional tumors (70%), degree of cell differentiation (80%) and higher incidence of multifocality in infiltrative growth of the primary tumor support the existing hypophysis about the role of intraorgan metastasizing as the underlying cause of multifocal lesions. Also, the study confirmed low preoperative detection of multifocality: 1.8% preoperatively and 19.2% under investigation.
References
- Аляев Ю. Г., Крапивин А. А. Резекция почки при раке. М.: Медицина; 2001.
- Переверзев А. С. Хирургия опухолей почек и верхних мочевых путей. Харьков; 1997.
- Klelscher В. A., Qwian J., Botswick D. G. et al. Prospective analysis of multifocality in renal carcinoma: influence of histologic pattern, grade, number, size, volume and DNA ploidy. J. Urol. (Baltimore) 1995; 153: 904-906.
- Lapini A., Carini M., Meliani E., Semi S. Disease reccurense after nefron-sparing surgery for renal cell carcinoma. Acta Urol. Ital. 1998; 12 (2): 61-66.
- Schlkhter A., Wunderlkh H., Junker K. et al. Where are the limits of elective nephron-sparing surgery in renal cell carcinoma? Eur. Urol. 2000; 37 (5): 517-520.
- Zigeuner R., Altziebler S., Schips L. et al. Nephron sparing surgery for renal cell carcinoma: risk factors for tumour progression. Ibid. 2001; 39 (5): 169.
- Russo P. Renal cell carcinoma: presentation, staging, and surgical treatment. Semin. Oncol. 2000; 27 (2): 160-176.
- Oneto F., Medica M., Giglio M. et al. Impact of internal tumour location sparing surgery. Eur. Urol. 2001; 39 (5): 169.
- Melissourgos N., Doumas K., Mtssini E. et al. Can nephron-sparing surgery be conditioned by tumour's multicentricity in renal cell carcinoma? Ibid. 2000; 37 (suppl. 2): 57.
- Hen H. W. Partial nephrectomy for unilateral renal carcinoma and a normal contralateral kidney: 10-year follow-up. J. Urol. (Baltimore) 1999; 161: 33-35.
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