BENIGN MIMICS OF PROSTATIC ADENOCARCINOMA


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Resumo

Prostate cancer occupies 2nd place on the prevalence and 6th place on mortality among all cancers in men. That is not to deny the social importance of prostate cancer, but attention is drawn to significant advantage of newly detected cases above the cancer-specific mortality. «Gold standard» for diagnosis includes morphological study of tissue fragments after transrectal multifocal prostate biopsy. The importance of the differential diagnosis is particularly relevant when analyzing fragments of prostate tissue obtained from biopsies as a false positive result may cause unnecessary and excessive treatment. This article presents the most common benign processes that can simulate various grade adenocarcinoma. Awareness about the presence of such cancer mimics and careful examination of micropreparations in most cases allows to come to the correct conclusion.

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Sobre autores

M. Kovylina

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

E. Prilepskaya

MSMSU n.a. A.I. Evdokimov

Email: prilepskayae@mail.ru
researcher at the Department of Urology

A. Govorov

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

V. Dyakov

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

K. Kolontarev

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

A. Vasiliev

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

A. Sidorenkov

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

P. Rasner

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

A. Glotov

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

D. Pushkar

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

V. Nikitaev

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

A. Pronichev

MSMSU n.a. A.I. Evdokimov

researcher at the Department of Urology

Bibliografia

  1. Ferlay J., Shin H.R., Bray F. et al. Globocan 2008: Cancer Incidence and Mortality Worldwide. IARC Cancer Base No. 10. Lyon, France: International Agency for Research on Cancer; 2010.
  2. Siegel R., Naishadham D., Jemal A. Cancer statistics, 2013. CA Cancer. J Clin. 2013;63:11-30.
  3. Schröder F.H., Hugosson J., Roobol M.J. et al. ERSPC Investigators. Prostate-cancer mortality at 11 years of follow-up. N Engl J Med. 201;366(11):981-990.
  4. Ilic D., Neuberger M.M., Djulbegovic M. et al. Screening for prostate cancer Cochrane Database Syst Rev. 2013;1:CD004720.
  5. Humphrey P.A. Prostate pathology. ASCP Press: 2004.

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