Specific features of lower urinary tract symptoms in men living in the moscow region. Results of the epidemiological study


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Introduction. Voiding disorders in men are manifested by various symptoms associated with impairment of the urinary flow along the urinary tract and worsening of the urinary bladder storage function. There is a considerable lack of data on the prevalence of LUTS, their severity, and correlation with data from objective studies in men in the Russian Federation in general and in the Moscow region in particular. Materials and methods. A prospective multicenter epidemiological study «Specific Features of Lower Urinary Tract Symptoms in Men Living in the Moscow Region» was conducted based on data acquired from April 1 to May 31, 2017 by an anonymous survey of 525 men (mean age 64.2+9.93 years old), residing in Moscow and presenting with complaints of urination disorders. The respondents answered questions of a specially developed 140-item questionnaire. All demographic and medical information was taken into account, including concomitant diseases and ongoing therapy. The patients filled out the IIEF, I-PSS, QoL, and AMS (Aging Male Screening) questionnaires. Results. Analysis the I-PSS scores showed that symptoms of the emptying phase predominated over the symptoms of the filling phase in all age groups. The most frequent complaints were «frequent urination» and «weak urine stream». Forty and 30% of respondents had moderate and severe LUTS, respectively. The remaining 30% of men had mild LUTS. Prostate volume was significantly greater than that reported in similar studies conducted in Asia, Europe and North America (mean 55.27 cm3). The level of total prostate-specific antigen (PSA) was known in 98.8% of patients over the age of 50 and averaged 3.87±4.41 ng/ml. The mean age at the first testing for total PSA in Moscow is 56.7+9.0 years. Conclusion. This study is the first epidemiological study of this scale and focus. Its findings can be used to compose a «portrait» of a standard patient and identify patterns that limit the extrapolation of international epidemiological studies to the population of Russian patients. It seems necessary to develop an updated LUTS management strategy, taking into account the identified national characteristics.

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Sobre autores

D. Pushkar

A.I. Evdokimov MSUMD

Corr.-Member of the RAS, Dr.Med.Sci., Prof., Head of the Department of Urology, A.I. Evdokimov MSUMD, Chief Urologist of Minzdrav of Russia, Chief Urologist of Moscow

P. Rasner

A.I. Evdokimov MSUMD

Email: dr.rasner@gmail.com
Dr.Med.Sci., Prof. at the Department of Urology, A.I. Evdokimov MSUMD, Head of the Department of Urology №4, S.I. Spasokukotsky Municipal Clinical Hospital of the Moscow HD

D. Kotenko

A.I. Evdokimov MSUMD

Ph.D., Staff Member at the Department of Urology

A. Gerasimov

I.M. Sechenov First MSMU of Minzdrav of Russia (Sechenov University)

Dr. Phys.-Math. Sci., Professor, Head of the Department of Medical Informatics and Statistics, the Faculty of Medicine and Prevention

S. Shabalkin

A.I. Evdokimov MSUMD

Staff Member at the Department of Urology

Bibliografia

  1. Пушкарь Д.Ю., Раснер П.И. Урология. Российские Клинические Рекомендации. Глава 1. Симптомы нижних мочевых путей и доброкачественная гиперплазия предстательной железы. Российские клинические рекомендации под ред. Ю.Г. Аляева, П.В. Глыбочко, Д.Ю. Пушкаря М.: МедФорум. 2018;13-43
  2. Вишневский А.Е., Пушкарь Д.Ю. Патогенез ноктурии у больных доброкачественной гиперплазией простаты. Клин, фармакология и терапия. 2005;2:45-48
  3. Irwin D.E., Milsom I., Hunskaar S., Reilly K., Kopp Z., Herschorn S., Coyne K., Kelleher C., Hampel C., Artibani W., Abrams P. Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study. Eur Urol. 2006;50(6):1306-1314.
  4. Milsom I., Abrams P., Cardozo L., Roberts R.G., Thüroff J., Wein A.J. How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study. BJU Int. 2001;87(9):760- 766.
  5. Montorsi F., Roehrborn C., Garcia-Penit J., Borre M., Roeleveld T.A., Alimi J.C., Gagnier P., Wilson T.H. The effects of dutasteride or tamsulosin alone and in combination on storage and voiding symptoms in men with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH): 4-year data from the Combination of Avodart and Tamsulosin (CombAT) study. BJU Int. 2011;107(9):1426-1431.
  6. Казилов Ю.Б., Гаджиева З.К., Мугутдинов Т.М., Казилов Б.Р. Распространенность различных нарушений мочеиспускания у жителей Республики Дагестан. Урология. 2016;4:42-47
  7. Пушкарь Д.Ю., Раснер П.И., Цуканов А.Ю., Куприянов Ю.А., Калашян А.А. Исследование знаний пациентов по выявлению рака простаты. Урология. 2010;2:48-52
  8. Malmsten U.G., Milsom I., Molander U., Norlen L.J. Urinary incontinence and lower urinary tract symptoms: an epidemiological study of men aged 45 to 99 years. J Urol. 1997;158:1733-1737.
  9. Rhodes T., Girman C.J., Jacobson D.J et al. Longitudinal prostate volume in a community-based sample: 7-year follow-up in the Olmsted County study of urinary symptoms and health status among men. J Urol. 2000;163:248, A1105.
  10. Jacobsen S.J., Jacobson D.J., Girman C.J., Roberts R.O., Rhodes T., Guess H.A., Lieber M.M. Natural History of Prostatism: Risk Factors for Acute Urinary Retention. The Journal of Urology. 1997;158(2):481-487.
  11. Jacobsen S.J., Jacobson D.J., Girman C.J., Roberts R.O., RhodesT., Guess H.A., Lieber M.M. Treatment for benign prostatic hyperplasia among community dwelling men: the Olmsted County study of urinary symptoms and health status. J Urol. 1999;162(4):1301-1306.
  12. Jacobsen S.J., Jacobson D.J., McGree M.E., St Sauver J.L., Klee G.G., Girman C.J., Lieber M.M. Sixteen-year Longitudinal Changes in Serum Prostate-specific Antigen Levels: the Olmsted County Study. Mayo Clin Proc. 2012;87(1):34-40.
  13. Shi-Jun Zhang, Hai-Ning Qian, Yan Zhao, Kai Sun, Hui-Qing Wang, Guo-Qing Liang, Feng-Hua Li, Zheng Li. Relationship between age and prostate size. Asian Journal ofAndrology. 2013;15:116-120.
  14. Berges R., Oelke M. Age-stratified normal values for prostate volume, PSA, maximum urinary flow rate, IPSS, and other LUTS/BPH indicators in the German male community-dwelling population aged 50 years or older. World J Urol. 2011;29(2):171-178.
  15. McConnell J.D., Roehrborn C.G., Bautista O.M., Andriole G.L. Jr., Dixon C.M., Kusek J.W., Lepor H., McVary K.T., Nyberg L.M. Jr., Clarke H.S., Crawford E.D., Diokno A., Foley J.P., Foster H.E., Jacobs S.C., Kaplan S.A., Kreder K.J., Lieber M.M., Lucia M.S., Miller G.J., Menon M., Milam D.F., Ramsdell J.W., Schenkman N.S., Slawin K.M., Smith J.A. The Long-Term Effect of Doxazosin, Finasteride and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia. N Engl J Med. 2003;349(25):2387-2398.
  16. Marberger M. The MTOPS Study: New Findings, New Insights, and Clinical Implications for the Management of BPH. Eur Urol. 2006;5:628-633.
  17. De Nunzio C., Aronson W., Freedland S.J., Giovannucci E., Parsons J. The correlation between metabolic syndrome and prostatic diseases. Eur Urol. 2012;61(3):560-570.
  18. Moul S., Mc Vary K.T. Lower urinary tract symptoms, obesity and the metabolic syndrome. Curr Opin Urol. 2010;20:7-12.
  19. Ogden C.L., Carroll M.D., Fryar C.D., Flegal K.M. Prevalence of Obesity Among Adults and Youth: United States, 2011-2014. NCHS Data Brief. 2015;(219):1-8.

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