Pathomorphological criteria for the differential diagnosis of leukoplakia and chronic recurrent papillomavirus cystitis
- Autores: Ibishev K.S.1, Lapteva T.O.2, Todorov S.S.1, Goncharov I.D.1, Alkhashash A.M.1, Mamedov V.K.1
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Afiliações:
- Federal State Budgetary Educational Institution of Higher Education «Rostov State Medical University» of the Ministry of Health of Russia
- State Autonomous Institution of the Rostov Region «Regional Consultative and Diagnostic Center» of the Ministry of Health of Russia
- Edição: Nº 3 (2024)
- Páginas: 28-32
- Seção: Original Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/634979
- DOI: https://doi.org/10.18565/urology.2024.3.28-32
- ID: 634979
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Resumo
Introduction: According to the literature of recent years, there has been an increased interest in non-oncological diseases of the bladder, between which differential diagnostics have to be carried out in order to determine a plan for the diagnosis and treatment of patients with these nosologies. There are often certain difficulties in the differential diagnosis of some forms of viral cystitis and leukoplakia
Objective: to determine pathomorphological criteria for the differential diagnosis of leukoplakia and chronic recurrent papillomavirus cystitis.
Materials and methods: The prospective study included 85 sexually active patients aged 20–45 years, who were divided into two groups depending on the etiological factor. Patients of group I (n=70) – with chronic recurrent cystitis (CRC) of papillomavirus (PV) etiology, group II (n=15) – with leukoplakia. All patients were examined in accordance with the recommendations of the European Association of Urology (EAU) and the Russian Society of Urology (ROU); an additional endoscopic examination of the bladder (cystoscopy) was performed, followed by a morphological examination of the bladder biopsy.
Results: A morphological examination of biopsy tissue in all patients of group I revealed koilocytic transformation of the urothelium combined with non-keratinizing metaplasia of the urothelium, and in patients of group II, in all cases, keratinizing metaplasia of the urothelium with hyperkeratosis was detected.
Conclusion: Morphological examination is the gold standard in differential leukoplakia and chronic recurrent papillomavirus cystitis
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Sobre autores
Kh. Ibishev
Federal State Budgetary Educational Institution of Higher Education «Rostov State Medical University» of the Ministry of Health of Russia
Autor responsável pela correspondência
Email: ibishev22@mail.ru
ORCID ID: 0000-0002-2954-842X
M.D., Dr. Sc. (Med), Full Prof., Prof. Dept. of Urology, Pediatric Urology & Reproductive Health
Rússia, Rostov-on-DonT. Lapteva
State Autonomous Institution of the Rostov Region «Regional Consultative and Diagnostic Center» of the Ministry of Health of Russia
Email: Lto-96@yandex.ru
ORCID ID: 0000-0002-6544-6113
M.D., Pathologist, Pathology Division
Rússia, Rostov-on-DonS. Todorov
Federal State Budgetary Educational Institution of Higher Education «Rostov State Medical University» of the Ministry of Health of Russia
Email: sertodorov@gmail.com
ORCID ID: 0000-0001-8476-5606
Dr. Sc. (Med.), Associate Professor of the Department of Operative Surgery, Clinical Anatomy and Pathological Anatomy, head of the morphological department of the clinic, pathologist of the highest category
Rússia, Rostov-on-DonI. Goncharov
Federal State Budgetary Educational Institution of Higher Education «Rostov State Medical University» of the Ministry of Health of Russia
Email: ilagoncarov11250@gmail.com
ORCID ID: 0009-0005-0770-7230
resident of the Department of Urology and Human Reproductive Health (with a course of pediatric urology-andrology)
Rússia, Rostov-on-DonA. Alkhashash
Federal State Budgetary Educational Institution of Higher Education «Rostov State Medical University» of the Ministry of Health of Russia
Email: Ahmadalhashash95@gmail.com
ORCID ID: 0009-0002-8983-3107
postgraduate student of the Department of Urology and Human Reproductive Health (with a course of pediatric urology-andrology)
Rússia, Rostov-on-DonV. Mamedov
Federal State Budgetary Educational Institution of Higher Education «Rostov State Medical University» of the Ministry of Health of Russia
Email: mamedov1007@yandex.ru
ORCID ID: 0000-0001-5508-4510
M.O. Urologist, Postgraduate student, Dept. of Urology and Human Reproductive Health (with Podiatrie Urology and Andrology Course)
Rússia, Rostov-on-DonBibliografia
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