Определение лактоферрина при уретритах и уретропростатитах

Аннотация

An immunochemical study of prostatic secretions in 97 patients with urethritis and iirethroprostatitis has detected a significant rise of lactoferrin level in mixed infections (trichomonads+chlamydia and trichomonads+uroplasma - 17 patients) versus control (14 healthy males) and group as a whole. In the control group a mean lactoferrin level was 5l.2±8.4 mg/1 (12 mg/1-67.3 mg/1), in the group as a whole 106±41.5 mg/1 (19.5 mg/1 to 334.8 mg/1) in patients with mixed infection 221.25 (102.9 mg/1 to 334.8 mg/1). The assessment of diagnostic significance of the immunochemical test for lactoferrin in detection of mixed infections in urethritis and iirethroprostatitis has shown that in threshold level of 150 mg/1 the test's specificity was 87.5%, sensitivity 94.1%, effectiveness 88.65%, prognostic value of positive result 61.5%, of negative result 98.59%; in threshold level 200 mg/1 the respective values were 100, 52.9, 91.75, 100 and 90.9%. Practical application of the proposed immunochemical test in detection of mono- and mixed infection is discussed.