Размеры рака почки. Клинико-морфологические корреляции
- Авторы: Серегин АВ1, Лоран ОБ1, Ашугян ВР1, Seriogin AV1, Loran OB1, Ashugyan VR1
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Учреждения:
- Выпуск: № 3 (2009)
- Страницы: 42-48
- Раздел: Статьи
- URL: https://journals.eco-vector.com/1728-2985/article/view/277399
- ID: 277399
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Аннотация
To reveal correlations between a renal tumor size and its clinical and morphological characteristics, we retrospectively analysed 263 case histories of patients with renal cell cancer. At a univariate analysis a maximal renal tumor size as a continuous variable significantly correlated with tumor differentiation, histological involvement of regional lymph nodes, presence of tumor necrosis, venous thrombosis, invasion into the collecting system, severity of clinical symptoms, 3- and 5-year cancer-specific survival. An increase of a tumor size, either as a continuous variable or a categorical one is accompanied with enhancement of tumor properties determining the outcome. The inclusion of a tumor size as a continuous parameter in the staging systems may have in the future a significant impact on accuracy of prediction of a renal cell cancer course and outcome, on specification of indications for various treatments.
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