RELATIONSHIP OF SYSTEMIC FACTORS IN THE PATHOGENESIS OF CHRONIC PELVIC PAIN SYNDROME IN MEN
- 作者: Tyuzikov I.A1
-
隶属关系:
- 期: 编号 6 (2012)
- 页面: 48-51
- 栏目: Articles
- URL: https://journals.eco-vector.com/1728-2985/article/view/279639
- ID: 279639
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
详细
Survey of 250 men with category III chronic pelvic pain syndrome/ chronic prostatitis (CPPS/CP-III) showed that the urological disease often proceeds against the background of obesity (29.6%), androgen deficiency (38.4%), increased tone of sympathetic nervous system (62.9%) and the activation of the plasma lipid peroxidation system (oxidative stress) (100%), with significant correlations between these factors. Working hypothesis was formulated; according this hypothesis, the components of metabolic syndrome in men and associated systemic reactions of sympathetic hyperactivity, oxidative stress, and androgen deficiency play an important role in the pathogenesis of CPPS/CP-III. This allows to consider CPPS/CP-III as an interdisciplinary complex issue of men's health and to review the existing traditional approaches to its diagnosis, treatment and prevention.
全文:
参考
- Gorbachinsky I. Metabolic Syndrome and Urological Deseases. Rev. Urol. 2010; 12(4):157—80.
- Gustafson B., Hammarstedt A., Andersson C.X. et al. Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2007; 27: 2276— 2283.
- Srikanthan P., Karlamangla A.S. Relative Muscle Mass Is Inversely Associated withlnsulin Resistance and Prediabetes. Findings from The Third National Health and Nutrition Examination Survey. J Clin Endocrin Metab [First published ahead of print] 2011: doi: 10.1210/jc.2011—0435.
- Weinberg J.M. Lipotoxicity. Kidney Int 2006; 70: 1560—1566.
- Коган М.И., Белоусов И.И., Шангичев А.В. Синдром хронической тазовой боли/ХП III: текущая точка зрения Ростовского медицинского университета. Материалы IV Всероссийского конгресса “Мужское здоровье”. М., 2008: 101—104.
- Корнеев И.А., Глазнева С.Ю. Уровень тестостерона и расстройства мочеиспускания у больных с доброкачественной гиперплазией предстательной железы. Материалы IV Всероссийского Конгресса “Мужское здоровье”. М., 2008: 49—50.
- Курникова А.А., Шукшина Л.М. Взаимосвязь метаболических параметров и факторов воспаления при возрастном гипогонадизме. Материалы VI Российского конгресса "Мужское здоровье". М., 2010: 305—306.
- Лоран О.Б., Пушкарь Д.Ю., Сегал А.С. Наше понимание хронического простатита. Фарматека. 2002; 10: 69—75.
- Калинченко С.Ю., Тюзиков И.А. Практическая андрология. М.: Практическая медицина. 2009, 400 с.
- Goncharov N.P., Katsya G.V., Chagina N.A. et al. Three definitions of metabolic syndrome applied to a sample of young obese men and their relation with plasma testosterone. Aging Male 2008; 11:118—122.
- Чупрына П.С., Деревянченко В.И., Щелков С.В. Доброкачественная гиперплазия простаты, осложненная ОЗМ, и уровень тестостерона крови. Материалы IV Всероссийского Конгресса “Мужское здоровье”. М., 2008: 66—67.
- Corona G., Manucci E., Forti G. et al. Hypogonadism, ED, metabolic syndrome and obesity: a pathological link supporting cardiovascular diseases. Int. J. Androl. 2009;32:587—588.
- Demir O., Akgul К., Akar Z. Association between severity of lower urinary tract symptoms, erectile dysfunction and metabolic syndrome. Aging. Male. 2009;12:29—34.
- Fibbi B., Penna G., Morelli A. Chronic inflammation in the pathogenesis of benign prostatic hyperplasia. Int. J. Androl. 2010; 33: 475—488.
- Kupelian V., McVary K.T., Kaplan S.A. Association of lower urinary tract symptoms and the metabolic syndrome: results from the Boston Area Community Health Survey. J. Urol. 2009;182: 616—624.
- McVary K.T., Rademaker A., Lloyd G.L. et al. Autonomic nervous system overactivity in men with lower urinary tract symptoms secondary to benign prostatic hyperplasia. J. Urol. 2005;174(4), Pt. 1:1327—1433.
补充文件
