Experimental validation of ND:YAG laser coagulation of the bladder tissue


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Interstitial laser coagulation (ILC) is one of the minimally invasive and minimally traumatic methods for the destruction of small lesions in various organs and tissues. Selection of the optimal operation and exposure mode is critical for the safe use of ILC in clinical practice. The in-vivo study of ILC effects on bladder tissue was carried out in 6 rabbits weighing less than 3 kg. Macroscopic and microscopic analysis of the tissue was done directly after the ILK procedure, on days 3 and 7, 14 and 21 following specimen collection of experimental animals. Safety and efficacy of ND: YAG laser impact on bladder tissues were confirmed by morphological study, which established phasing and extent of changes in the bladder tissues. The results allow us to recommend ILC application for the destruction of small size bladder tumors without impairment of the bladder functions, as well as for the treatment of bottom after transurethral resection of bladder cancer.

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作者简介

E. Rasshupkina

Russian Medical Academy of Postgraduate Education of Minzdrav of Russia

Email: doctor-ras@bk.ru
Urologist, Senior Laboratory Assistant of Department of Endoscopic Urology of RMAPE of Minzdrav of Russia

O. Teodorovich

Russian Medical Academy of Postgraduate Education of Minzdrav of Russia; Research Clinical Center of JSC «Russian Railways»

D. Kochiev

General Physics Institute n.a. A.M. Prokhorov of RAS

Ju. Andreeva

Russian Medical Academy of Postgraduate Education of Minzdrav of Russia

M. Shatohin

Russian Medical Academy of Postgraduate Education of Minzdrav of Russia; Research Clinical Center of JSC «Russian Railways»

G. Borisenko

Russian Medical Academy of Postgraduate Education of Minzdrav of Russia

参考

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