Use of high-dose vitamin C and Suby G solution in the treatment of encrusted cystitis

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This article describes a clinical case of the successful use of high doses of vitamin C and Suby G solution to reduce urine acidity in a patient with encrusted cystitis. The previously used combination of oral methionine intake and intravesical instillations of a 3% aqueous boric acid solution was ineffective. As part of comprehensive therapy, transurethral resections of bladder wall encrustations were performed, along with antibacterial therapy with vancomycin. The obtained results indicate the potential effectiveness of this combination; however, further clinical studies are needed to verify them.

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作者简介

Inga Kosova

Russian Medical Academy of Continuous Professional Education; Demikhov City Clinical Hospital (branch №2)

Email: kosovainga@mail.ru
ORCID iD: 0000-0002-0051-0583

M.D., Dr. Med. Sc., Assoc. Prof., Professor at the Department of Urology and Surgical Andrology, Urologist at the Department of Urology (branch №2)

俄罗斯联邦, Moscow; Moscow

Vagan Barsegian

European Medical Center

编辑信件的主要联系方式.
Email: vaganbarsegyan@gmail.com
ORCID iD: 0000-0003-0592-3181

M.D., Ph.D., Urologist, Urology Clinic

俄罗斯联邦, Moscow

Oleg Loran

Russian Medical Academy of Continuous Professional Education

Email: oleg_loran@gmail.com
ORCID iD: 0000-0002-7531-1511

Academician of the RAS, Dr. Med. Sc, Professor, Chief of the Department of Urology and Surgical Andrology

俄罗斯联邦, Moscow

Vladimir Saenko

Sechenov University

Email: saenko_vs@staff.sechenov.ru
ORCID iD: 0000-0003-3107-8161

M.D., Dr. Med. Sc., Assoc. Prof., Professor at the Institute of Urology and Human Reproductive Health

俄罗斯联邦, Moscow

Dmitriy Kolbasov

Demikhov City Clinical Hospital (branch №2)

Email: urology68@rambler.ru

M.D., Ph.D., Chief of the Department of Urology №2

俄罗斯联邦, Moscow

Nikolay Grigoriev

European Medical Center

Email: ngrigoriev@emcmos.ru

M.D., Dr. Med. Sc., Professor, Chief of the Urology Clinic, Chief of the Department of Urology, EMC Medical School

俄罗斯联邦, Moscow

参考

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  2. Fu JG, Xie KJ. Successful treatment of encrusted cystitis: A case report and review of literature. World J Clin Cases. 2020 Sep 26;8(18):4234-4244. doi: 10.12998/wjcc.v8.i18.4234. PMID: 33024784; PMCID: PMC7520765.
  3. Gadzhiev N.K., Malikiev I.E., Obidnyak V.M. et al. The Problem of Clinical Diagnostics and Treatment of Incrusting Cystitis. Urology. 2022;5:142–146. doi: 10.18565/urology.2022.5.142-146. EDN PJJTYW. Russian (Гаджиев Н.К., Маликиев И.Е., Обидняк В.М. и др. Проблема клинической диагностики и лечения инкрустирующего цистита. Урология. 2022;5:142–146. doi: 10.18565/urology.2022.5.142-146. EDN PJJTYW).
  4. Kosova I.V., Barsegian V.A., Loran O.B. et al. Etiological factors in the development of urinary disorders in women. Consilium Medicum. 2022;24(7):451–455. doi: 10.26442/20751753.2022.7.201791. EDN CPEKHD. Russian (Косова И.В., Барсегян В.А., Лоран О.Б. и др. Этиологические факторы развития нарушений мочеиспускания у женщин. Consilium Medicum. 2022;24(7):451–455. doi: 10.26442/20751753.2022.7.201791. EDN CPEKHD).
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  7. Perrucci E., Lancellotta V., Benedetto M.D., Palumbo I., Matrone F., Chiodi M., Lombi R., Marcantonini M., Mariucci C., Aristei C. Encrusted cystitis after definitive radiotherapy for cervical cancer: a case report. J Contemp Brachytherapy. 2016;8(6):541–543. doi: 10.5114/jcb.2016.62958. PMID: 28115961; PMCID: PMC5241373.
  8. Benoit G., Eschwege P., Paradis V., Droupy S., Nordmann P., Charpentier B. Successful treatment of encrusted pyelitis in a renal transplant with local acidification and surgical ileocaliceal anastomosis. J Urol. 1999;162(4):1369–70. PMID: 10492200.

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2. Fig. 1. CT scan of the urinary system organs with intravenous contrast. A — the proximal curl of the internal ureteral stent on the right, B — multiple concretions of the left kidney

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3. Fig. 2. CT scan of the urinary system organs with intravenous contrast. Uneven calcification of the bladder mucosa

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4. Fig. 3. Cystoscopic picture. Encrustations on the mucous membrane of the bladder

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5. 4. Cystoscopic picture 2 months after the start of treatment

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