Selenium-containing nanoscale systems stabilized with hydroxyethyl cellulose: synthesis, stability, properties

In this work, the synthesis and study of selenium-containing nanoscale systems stabilized with hydroxyethyl cellulose B30K were carried out. At the first stage, the methodology for the synthesis of selenium–containing nanosystems was optimized, where selenic acid was used as a precursor, ascorbic acid as a reducing agent, and hydroxyethyl cellulose B30K as a stabilizer. As a result, it was found that optimal concentrations and weight of the components are: C (H₂SeO₃) = 0.3536 mol/l; m (hydroxyethyl cellulose) = 0.015 g; C (C₆H₈O₆) = 0.7938 mol/l. Computer modeling was performed, in which it was established that interaction of selenium with hydroxyethyl cellulose B30K is energetically advantageous (∆E ≥ 2399.586 kcal/mol) and chemically stable (0.076 ≤ n ≤ 0.093 eV), and the most likely interaction option was determined. At the next stage, the technological parameters of the reaction medium were optimized, as a result of the data obtained, it was found that the optimal parameters are: pH = 11, t = 25 °C, τ = 15 min. Further, influence of pH of the medium on selenium-containing nanoscale systems stability was studied, as a result it was found that samples are most stable at pH = 6.8.