Insulin pump therapy - a way to achieve clinical and metabolic compensation of the disease in children and adolescents with type 1 diabetes mellitus

Abstract

We consider the advantages and disadvantages of intensified insulin therapy in children and adolescents with type 1 diabetes mellitus (type 1 diabetes), in terms of opportunities to achieve and maintain compensation for this disease. The expediency of translation of this population of patients with type 1 diabetes for insulin pump therapy (IPT) is discussed. The results of evaluating the effectiveness of prolonged IPT use in 105 children and adolescents with type 1 diabetes with poor disease control before the application of this method of treatment are presented. It has been established that the IPT is effective way to improvement of clinical and metabolic compensation of type 1 diabetes in children and adolescents with poor disease control. Its appointment enhances the indices of glycemic control, allows reducing the average daily dose of insulin, prevents the development of severe hypoglycemia and episodes of diabetic ketoacidosis requiring hospitalization, and increases the quality of life of patients.

References

  1. Diabetes Control and Complications Trial Research Group: Effect of intensive diabetes treatment on the development and progression of long-term complications in adolescents with insulin-dependent diabetes mellitus: Diabetes Control and Complications Trial. J Pediatr 1994;125(2):177-88.
  2. Rewers M, Pihoker C, Donaghue K, et al. Assessment and monitoring of glycemic control. Ispad consensus guidelines 2007. Pediatr Diabetes 2007;8:25-29.
  3. Safety and Effectiveness of Insulin Pump Therapy in Children and Adolescents with Type 1 Diabetes. Diabetes Care 2003;26:1142-46.

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