Use of somastatin analogues in the treatment of patients with acromegaly: options for the drug Somatuline® Autogel® use


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Abstract

We consider the modern potentials for use of selective somatostatin analogs in the treatment of acromegaly. The comparative data for the analogues widely used in clinical practice (preparations of octreotide and lanreotide) are presented. The results of clinical studies aimed to evaluation of effectiveness of selective analogue of somatostatin with prolonged action - Somatuline®Autogel® - in acromegaly are considered. Mechanisms of antisecretory and antiproliferative effects of the drug and the optimal scheme of its use are discussed.

References

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