Oxidative stress associated with cerebrovascular dysfunction: possibilities of therapy
- Authors: Vorob'eva OV1, Vorobyova O1
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Affiliations:
- Issue: No 5 (2010)
- Pages: 98-102
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/278334
- ID: 278334
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Abstract
In recent years, there are more and more evidences that the disease of old age and oxidative stress are associated with significant cerebrovascular changes. Peroxidation is one of the most important parts of gene activation reactions coding apoptosis, which suggests therapeutic benefit of antioxidants in the acute and chronic stages of cerebral ischemia. At least three main effects of Mexidol - antioxidant, antihypoxic and hypolipodemic - may be useful in the treatment of ischemic brain damage. The groups of patients with dyscirculatory encephalopathy from the perspective of advisability of mexidol administration are discussed.
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