ХРОНИЧЕСКИЙ ГЕПАТИТ С У ЛИЦ ПОЖИЛОГО ВОЗРАСТА


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Аннотация

Обсуждаются эпидемиология, особенности течения и осложнений хронического гепатита С (ХГС) у лиц пожилого возраста. Представлены показания и возможные противопоказания к назначению противовирусной терапии (ПВТ) у этой категории больных. Отмечается, что у пожилых больных ХГС часто отмечаются неудовлетворительные результаты ПВТ, что м. б. обусловлено сочетанием целого ряда неблагоприятных факторов (продвинутый фиброз печени, инфицирование 1 генотипом HCV, высокая вирусная нагрузка, наличие стеатогепатита метаболического и алкогольного генеза, низкая приверженность ПВТ в связи с плохой переносимостью лечения и т.д.). Вопрос о целесообразности ПВТ у больного ХГС пожилого возраста с оценкой соотношения польза/риск должен быть решен в каждом наблюдении в индивидуальном порядке с учетом всех факторов (сопутствующие заболевания, активность ХГС, стадия заболевания и т. д.).

Об авторах

Z Burnevich

T N Lopatkina

Эдуард Збигневич Бурневич

Кафедра терапии и профзаболеваний ММА им. И.М.Сеченова, Москва

Кафедра терапии и профзаболеваний ММА им. И.М.Сеченова, Москва

Татьяна Николаевна Лопаткина

Кафедра терапии и профзаболеваний ММА им. И.М.Сеченова, Москва

Кафедра терапии и профзаболеваний ММА им. И.М.Сеченова, Москва

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