Intraintestinal metabolism disturbances in malabsorption syndrome in children: general regularities and ways of correction


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Abstract

Disorders of intestinal absorption associated with changes in the function of intestinal mucosa of different origin lead to significant changes in intestinal metabolism, particularly determining the development of the main symptom of this condition - the violations of stool consistency. Meanwhile, in bowel lumen the metabolism of carbohydrates, proteins, fats and bile acids is violated, that causes secondary disorders of the digestive function, and aggravates the course of primary pathological process. Treatment of the causes of malabsorption in combination with substitution therapy, including highly active preparations of pancreatic enzymes, is the main way in the correction of previously mentioned conditions.

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