PROGNOSTIC SIGNIFICANCE OF HIGH LEVELS OF CYTOKINES AND EMOTIONAL DISORDERS IN PATIENTS WITH CORONARY HEART DISEASE
- Authors: Averin Y.Y.1, Chernov SI1, Chernova S.I.1, Averin E.E.1
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- Issue: No 13 (2010)
- Pages: 109-111
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/278554
- ID: 278554
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Abstract
The levels of inflammatory cytokines, prevalence, severity and dynamics of depression were evaluated in patients with coronary heart disease (CHD). Increased concentrations of interleukin-1b, interleukin-6 and tumor necrosis factor-α were typical for the most severe forms of atherosclerotic coronary artery disease. Among patients with severe clinical manifestations of coronary artery disease, highest prevalence and severity of depression were detected. Maximum number of cases of depression was identified among patients with multivessel coronary pathology. Such patients require the administration of immunomodulating agents and inclusion of antidepressants in the scheme of treatment.
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