MONOCLONAL ANTIBODIES BEVACIZUMAB (AVASTIN (R)) IN COMBINATION THERAPY OF POORLY DIFFERENTIATED GLIAL TUMORS OF CENTRAL NERVOUS SYSTEM IN CHILDREN (LITERATURE REVIEW AND OWN EXPERIENCE)


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Abstract

Currently, treatment of malignant (poorly differentiated) glial brain tumors in children is most demanding task in pediatric neurooncology. Used in the present study for treatment of 17 children with glioblastomas and anaplastic astrocytomas of the central nervous system Bevacizumab (Avastin) in combination with cytotoxic drugs showed good tolerability and relatively high efficacy, reflected in increasing overall survival compared with published data.

References

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