ANEMIC SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE


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Abstract

The reasons for reduction of hemoglobin level in patients with chronic heart failure (CHF) are numerous and varied. Possible causes of the decrease in hemoglobin level in CHF are decreased kidney function (cardio-renal anemia syndrome); hemodilution; iron deficiency associated with chronic blood loss against the background of application of antiplatelet drugs; the use of angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists; activation of pro-inflammatory cytokines and associated bone marrow dysfunction. The variety of causes leading to a decrease in hemoglobin level in patients with CHF makes difficult a choice of treatment tactics. As a possible method of treatment of anemia in patients with CHF, the use of iron preparations (especially intravenous), EPO and their combination is considered.

References

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