THERAPEUTIC ASPECTS OF THE TREATMENT OF ULCER BLEEDING


Cite item

Full Text

Abstract

The article analyzes modern information about the clinical features and therapeutic principles of treatment of peptic ulcer complications. Despite the declining prevalence of peptic ulcer disease in Western Europe and North America, the frequency of complications of the disease does not tend to decrease. In Russian Federation, the situation is especially unfavourable. Therapeutic treatment options for ulcer bleeding are parenteral administration of high doses of modern proton pump inhibitors, timely diagnosis, and eradication of Helicobacter pylori infection.

References

  1. Sung JJ, Kuipers EJ, El-Serag HB. Systematic review: the global incidence and prevalence of peptic ulcer disease. Aliment Pharmacol Ther 2009;29(9):938-46.
  2. Bardhan KD, Williamson M, Royston C, et al. Admission rates for peptic ulcer in the trent region, UK, 1972--2000. changing pattern, a changing disease? Dig Liver Dis 2004;36(9):577-88.
  3. van Leerdam ME, Vreeburg EM, Rauws EA, et al. Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000 Am J Gastroenterol 2003;98(7):1494-99.
  4. Yavorski RT, Wong RK, Maydonovitch C, et al. Analysis of 3,294 cases of upper gastrointestinal bleeding in military medical facilities. Am J Gastroenterol 1995;90(4):568-73.
  5. Barkun A, Sabbah S, Enns R, et al. The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): Endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting. Am J Gastroenterol 2004;99(7):1238-46.
  6. Чернооков А.И., Яковченко А.В., Наумов Б.А. Эпидемиология сочетанных осложнений язвенной болезни желудка III типа и двенадцатиперстной кишки // Рос. журн. гастроэнтерологии, гепатологии, колопроктологии 2008. № 5. Прил. № 32. С. 42.
  7. Phillips AC, Polisson RP, Simon LS. NSAIDs and the elderly: toxicity and the economic implications. Drugs Aging 1997;10(2):119-30.
  8. Derry S, Loke YK. Risk of gastrointestinal haemorrhage with long-term use of ASA: meta-analysis. BMJ 2000;321(7270):1183-87.
  9. Barkun AN, Bardou M, Kuipers EJ, et al. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med 2010;152(2):101-13.
  10. Laine L, McQuaid KR. Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials. Clin Gastroenterol Hepatol 2009;7(1):33-47.
  11. Gisbert JP, Khorrami S, Carballo F, et al. Meta-analysis: Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcer. Aliment Pharmacol Ther 2004;19(6):617-29.
  12. Lau JY, Sung JJ, Lee KK, et al. Effect of intravenous omeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers. N Engl J Med 2000;343(5):310-16.
  13. Jensen DM, Pace SC, Soffer E, et al. Continuous infusion of pantoprazole versus ranitidine for prevention of ulcer rebleeding: a U.S. multicenter randomized, double-blind study. Am J Gastroenterol 2006;101(9):1991-99.
  14. Sung JJ, Barkun A, Kuipers EJ. Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding a randomized trial. Ann Intern Med 2009;150(7):455-64.
  15. Scheiman JM, Yeomans ND, Talley NJ, et al. Prevention of ulcers by esomeprazole in at-risk patients using non-selective NSAIDs and COX-2 inhibitors. Am J Gastroenterol 2006;101(3):701-10.
  16. Hartmann D, Eickhoff A, Damian U, et al. Effect of intravenous application of esomeprazole 40 mg versus pantoprazole 40 mg on 24-hour intragastric pH in healthy adults. Eur J Gastroenterol Hepatol 2007;19(2):133-37.
  17. Sung JJ. Marshall and Warren Lecture 2009: Peptic Ulcer Bleeding: An expedition of 20 years from 1989-2009. J Gastroenterol Hepatol 2010;25(2):229-33.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2012 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies