HOW TO OVERCOME THE EFFECTS OF "HYPERGLYCEMIC" MEMORY?
- Authors: Biryukova E.V.1, V Biryukova Y.1
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Affiliations:
- Issue: No 3 (2012)
- Pages: 58-62
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/279293
- ID: 279293
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Abstract
The article considers the questions of pathogenetic therapy of diabetic polyneuropathy. Pharmacological characteristics of thiamine and its fat-soluble analogue benfotiamine are discussed. Particular attention is paid to mechanisms of action of benfotiamine from a perspective of "hyperglycemic" memory. The results of clinical evaluation of efficacy and safety of benfotiamine are presented. By the example of Milgamma compositum (benfotiamine+pyridoxine) and Milgamma (B1, B6 and B12), high clinical efficacy of a combination of B vitamins is shown; potentials for their administration for the treatment of diabetics depending on the clinical course of distal polyneuropathy are discussed.
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