KOMBINIROVANNAYa ZhAROPONIZhAYuShchAYa TERAPIYa V PEDIATRIChESKOY PRAKTIKE
- 作者: Dronov I.A.1
-
隶属关系:
- 期: 编号 3s (2012)
- 页面: 23-26
- 栏目: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/279315
- ID: 279315
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
详细
Fever is one of the most common reasons for use of drug therapy in children. Usually, fever is the body's defensive reaction, which manifests itself in increasing the immune response, and preventing the growth of viruses and bacteria. Antifebrile therapy is usually necessary at a child’s temperature above 39 °C. The safest drugs, paracetamol and ibuprofen, are recommended as antipyretics for children. Clinical studies show that the combined use of these drugs (either simultaneously or successively) is more effective and has a better pharmacoeconomic results than the use of each drug alone. Therefore, the use of combination drug containing paracetamol offers promise.
关键词
全文:
参考
- Graneto J. Emergent Management of Pediatric Patients with Fever. Medicine: http://emedicine.medscape.com/article/801598, updated 08.11.2011.
- Тимченко В.Н., Павлова Е.Б. Современные подходы к терапии лихорадки у детей с инфекционной патологии // Лечащий врач 2008. № 8. С. 76-8.
- Геппе Н.А., Зайцева О.В. Представления о механизмах лихорадки у детей и принципах жаропонижающей терапии // РМЖ 2003. Т. 11. С. 31-7.
- Лихорадка у детей (клинические и патофизиологические аспекты). Учебнометодическое пособие / Под ред. С.А. Царьковой. Екатеринбург, 2010. 53 с.
- The management of fever in young children with acute respiratory infection in developing countries/WHO/ARI/93.90, WHO Geneva, 1993. 17. The Merck Manual 17th Ed., 1999.
- Pierce C.A., Voss B. Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review. Ann Pharmacother 2010; 44: 489-506.
- Southey E.R., Soares-Weiser K., Kleijnen J. Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever. Curr Med Res Opin 2009; 25: 2207-22.
- Li S.F., Lacher B., Crain E.F. Acetaminophen and ibuprofen dosing by parents. Pediatr Emerg Care 2000; 16(6): 394-97.
- Bilenko N., Tessler H., Okbe R., et al. Determinants of antipyretic misuse in children up to 5 years of age: a cross-sectional study. Clin Ther 2006; 28(5): 783-93.
- Alves J.G., Cardoso Neto F.J., Almeida C.D., et al. Dipyrone and acetaminophen: correct dosing by parents? Sao Paulo Med J 2007; 125(1): 57-9.
- American Academy of Pediatrics. Committee on Drugs. Acetaminophen toxicity in children. Pediatrics 2001; 108: 1020-24.
- Клиническая фармакология по Гудману и Гилману. М., 2006. 1648 с.
- Tanner T., Aspley S., Munn A., et al. The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol. BMC Clin Pharmacol 2010; 10: 10.
- Nabulsi M.M., Tamim H., Mahfoud Z., et al. Alternating ibuprofen and acetaminophen in the treatment of febrile children: a pilot study [ISRCTN30487061]. BMC Med. 2006; 4: 4.
- Paul I.M., Sturgis S.A., Yang C., et al. Efficacy of standard doses of Ibuprofen alone, alternating, and combined with acetaminophen for the treatment of febrile children. Clin Ther 2010; 32(14): 2433-40.
- Hay A.D., Costelloe C., Redmond N.M., et al. Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial. BMJ 2008; 337: a1302.doi: 10.1136/ bmj.a1302.
- Sarrell E.M., Wielunsky E., Cohen H.A. Antipyretic treatment in young children with fever: acetaminophen, ibuprofen, or both alternating in a randomized, double-blind study. Arch Pediatr Adolesc Med 2006; 160(2): 197-202.
- Erlewyn-Lajeunesse M.D., Coppens K., Hunt L.P., et al. Randomised controlled trial of combined paracetamol and ibuprofen for fever. Arch Dis Child 2006; 91(5): 414-16.
- Hollinghurst S., Redmond N., Costelloe C., et al. Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): economic evaluation of a randomised controlled trial. BMJ 2008; 33 7: a 1490.doi: 10.1136/ bmj.a1490.
补充文件
