LACTULOSE (DUPHALAC) IN THE TREATMENT OF HEPATIC ENCEPHALOPATHY IN CIRRHOTIC PATIENTS


Cite item

Full Text

Abstract

Minimal hepatic encephalopathy in liver cirrhosis requires special psychometric methods for its detection. Its presence significantly reduces the quality of life of patients with chronic diffuse liver diseases. The article discusses the early use of pathogenetic therapy for the correction of minimal hepatic encephalopathy aiming to prevention an obvious encephalopathy, improvement of quality of life of cirrhotic patients and their survival.

References

  1. Butterworth RF. Complications of Cirrhosis.III. Hepatic encephalopathy. J Hepatol 2000;32(1):171-80.
  2. Лопаткина Т.Н, Байкова Т.А. Минимальная печеночная энцефалопатия при циррозе печени и раннее назначение дюфалака // Фарматека 2012. № 2. С. 66-70.
  3. Coon HO. Assessment of the severity of hepatic encephalopathy. In: Rodes J, Arroyo V, eds. Therapy in liver diseases. Barselona: Edictions doyma, 1992:277-91.
  4. Бурневич Э.З., Лопаткина Т.Н., Краснова М.С. Печеночная энцефалопатия при циррозе печени // Гепатологический форум 2008. № 2. С. 19-24.
  5. Абдуллаев С.М. Печеночная энцефалопатия: диагностика, профилактика и лечение // Клиническая гепатология 2007. № 3. С. 41-5.
  6. Schomerus H, Hamster W, Blunck H, et al. Latent portasystemic encephalopathy.1. Nature of cerebralfunctionaldefects and their effect on fitness to drive. Dig Dis Sci 1981;26:622-30.
  7. Romero-Gomez M, Boza F, Garcia-Valdecasas MS, et al. Subclinical hepatic encephalopathy predicts the development of overt hepatic encephalopathy. Am J Gastroenterol 2001;96:2718-23.
  8. Rikkers L, Jenro P, Rudman D, Friedes D. Subclinical hepatic encephalopathy: detection, prevalence and relationship to nitrogen metabolism. Gastroenterology 1978;75:462-69.
  9. Иваников И.О., Сюткин В.Е. Общая гепатология. М.,2003. С. 141-45.
  10. Абдуллаев С.М. Печеночная энцефалопатия: диагностика, профилактика и лечение // Клиническая гепатология 2007. № 3. С. 41-5.
  11. Zeng Z, Li YY. Effects of lactulose treatment on the course of subclinical hepatic encephalopathy. Zhonghua yixue za zhi 2003;83:1126-29.
  12. Dhiman RK, Sawhney IM, Chavla YK, et al. Efficacy of lactylose in cirrhotic patients with subclinical hepatic encephalopathy. Dig Dis Sciences 2000;45:1549-52.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies