STRATEGY FOR DIAGNOSIS AND TREATMENT OF ALCOHOLIC LIVER DISEASE


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Abstract

Alcoholic liver disease (ALD) remains the leading cause of complicated diseases of this organ and high mortality worldwide. In economically developed countries, cirrhosis is one of the leading causes of death in the working-age adults. Etiology of cirrhosis can not be determined approximately in 10-35 % of patients. Such observations are referred to as cryptogenic cirrhosis. In fact, alcohol may be the cause of these cirrhoses. Dependence on alcohol and alcohol withdrawal syndrome are rarely observed in most patients with ALD that allows them to drink alcohol in large quantities for many years. Until the formation of cirrhosis, subclinical course of ALD is very typical for these patients. Therefore, timely treatment and prevention of cirrhosis are impossible. The ademetionine (Heptral) is drug of choice for the treatment of ALD. Treatment schemes with ademetionine are determined by the current stage of ALD (alcoholic steatosis, alcoholic hepatitis and alcoholic cirrhosis).

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T E Polunina

T E Polunina

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