EChENIE NEYTROPENII U ONKOLOGIChESKIKh BOL'NYKh


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Abstract

Neutropenia is one of the major side effects of cytostatic treatment of tumor diseases, contributing to the development of infectious complications. Prolonged neutropenia often does not allow chemotherapy as planned, and can lead to chemotherapy dose reduction, which ultimately reduces the effectiveness of antineoplastic therapy. Therefore, carefully evaluation of myelotoxic potential of modern chemotherapy regimens and identification of patients at high risk of febrile neutropenia, in need of prophylactic colony-stimulating factor, are required. The success of the treatment of febrile neutropenia depends on early detection of possible infection and early treatment.

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