Opyt primeneniya trastuzumaba v respublike Bashkortostan
- Authors: Sakaeva D.D1, Kunafina R.I1, Popova E.V1
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Affiliations:
- Issue: No 8 (2012)
- Pages: 74-76
- Section: Articles
- URL: https://journals.eco-vector.com/2073-4034/article/view/279568
- ID: 279568
Cite item
Abstract
This article discusses the practice of treatment of breast cancer with HER2/neu overexpression in the Republic of Bashkortostan. Trastuzumab was used as the drug that significantly improves the results of therapy. Patients were divided into two groups. In the study group, the drug was administered in adjuvant mode after the surgery, chemotherapy and radiation therapy. Times of recurrence and metastasis were analyzed in both groups. The use of trastuzumab in complex therapy allows to individualize the therapy for breast cancer and improve treatment outcomes.
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References
- Данные ежегодного отчета ГУЗ РКОД РБ.
- Slamon DJ, Clark GM, Wong SG, et al. Human breast cancer: correlation of relapse and survival with amplification of the Her-2neu oncogene. Science 1987;235: 177-82.
- Harari D, Yarden Y. Molecular mechanism underlaying ErbB/HER2 action in breast cancer. Oncogene 2000;19:6102-14.
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