Sovremennaya terapiya khronicheskogo zapora

Constipation is a frequent clinical syndrome, which occurs in approximately 20 % of the population. In recent decade, studies have contributed to a better understanding of the basic mechanisms of chronic constipation (CC), in particular its relationship to colonic transit and anorectal function. Many possible causes that affect the occurrence of constipation (metabolic, deficiency of fiber, medicines) should be taken into account during examination of the patient, and anorectal pathology should be excluded. Functional CC consists of three subtypes: slow-transit constipation, dyssynergic defecation and irritable bowel syndrome with predominance of constipation. Rome criteria are a useful guideline for the diagnosis of functional constipation. Treatment should be based on evidence-based diagnosis of CC variants. Enterokinetic agents such as prucalopride and lubiprostone should be used in the treatment of an inert colon. Advantages of biofeedbacktherapy should be used in the treatment of dyssynergic defecation.

chronic constipation, colonic transit, dyssynergic defecation, irritable bowel syndrome with predominance of constipation, enterokinetic agents, biofeedbacktherapy