Allergicheskiy rinit i bronkhial'naya astma: otsenka effektivnosti Lordestina

According to available data, 85-95 % of patients with bronchial asthma (BA) suffer a concomitant allergic rhinitis (AR), and BA is diagnosed in 20-50 % of patients with AR. Second generation antihistamines, one of which is desloratadine, play the leading role in the treatment of AR. The article presents the results of use of desloratadine (Lordestin) in 23 patients with BA combined with persistent AR. Pronounced positive effect of Lordestin was recorded in 19 patients. Reductions of AR symptoms was accompanied by disappearance or decrease in the amount of eosinophils in nasal smears and almost complete normalization of concentration of eosinophils in peripheral blood. The AR symptoms were decreased in 4 patients, but concentrations of eosinophils in nasal smears and in the blood remained the same. It is emphasized that the emergence of new highly effective, safe and economically available antiallergic drugs, such as Lordestin, improve access to quality treatment for more patients with AR in combination with BA.

allergic rhinitis, bronchial asthma, antihistamines, desloratadine, Lordestin