Terapevticheskie vozmozhnosti melatonina (Melaksena) pri insul'te


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Abstract

Melatonine is natural direct and indirect antioxidant that contributes to maintaining mitochondrial functions, has a good safety profile, non-toxic for human, and easy penetrates blood - brain barrier. Experimental studies confirm the efficacy of use of melatonin for the treatment of cerebral infarction: in rodents with experimental arterial occlusion, melatonin increases cerebral reperfusion, reduces cerebral edema, enhances neuroplasticity, and alters immune status. In this regard, the features of the use of melatonin in acute and subacute stages of cerebral infarction require further investigations.

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O. V Kotova

References

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