VLIYaNIE REVASKULYaRIZATsII U BOL'NYKh OSTRYM INFARKTOM MIOKARDA NA TEChENIE IShEMIChESKOY BOLEZNI SERDTsA V POSTINFARKTNOM PERIODE

The study was aimed to the evaluation of the influence of revascularization in patients with acute myocardial infarction on the incidence of in-hospital complications, coronary events, hospitalizations and deaths in the post-infarction period. At the hospital treatment stage, all patients (n = 301) were divided into 3 groups depending on performing the revascularization and its type. The group 1 consisted of patients who underwent thrombolytic therapy; group 2 included patients who underwent percutaneous coronary intervention with restoration of blood flow in the infarct-related artery; and group 3 consisted of patients without revascularization. Observations during the 1 year have shown that percutaneous coronary intervention in acute myocardial infarction allows to reduce the incidence of complications, recurrent coronary events, hospitalizations, and deaths. Revascularization using thrombolytic agents led only to a rare development of new angina during first months of observation compared with the tactics of optimal medical therapy without revascularization. Treatment compliance (especially for receiving dual antiplatelet therapy, β-blockers, statins, ACE inhibitors (ARA)) within one year after myocardial infarction had improved prognosis in all groups of patients. In patients with percutaneous coronary intervention in acute myocardial infarction, however, the number of recurrent coronary events was significantly lower than in patients without a history of myocardial revascularization, even in the absence of regular therapy.

revascularization, myocardial infarction, thrombolytic therapy, percutaneous coronary intervention