Neyroreparatsiya: sovremennye vzglyady na problemu


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Abstract

This review discusses the fundamental biological processes of neuroprotection, neurorestoration, and neurogenesis. Natural pathways of activation of protective mechanisms, counteracting damaging factors are described. Based on principles of evidence-based medicine, the possibility of pharmacological modulation of neurodegeneration/ neurorestoration, and prevention of apoptotic mechanisms are considered. Information on the effectiveness of the neuropeptide drug Cellex (polypeptides of the brain of pig embryos) in the treatment of stroke patients is provided. It is emphasized that the proposed mechanism of action of the drug enhances its therapeutic use: the time of his appointment to the patient with ischemic stroke is not limited to the first minutes or hours from onset, and extended for a much greater period of time.

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