Otsenka effektivnosti tioktovoy kisloty v korrektsii chuvstvitel'nykh narusheniy pri khronicheskoy vospalitel'noy demieliniziruyushchey poliradikulonevropatii


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Abstract

Sensory disorders are the main clinical manifestations of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), determining the disability of patients; so, the development of effective methods for their treatment is relevant and promising challenge. The results of study on the effectiveness and tolerability of 12-week course of treatment with thioctic acid in patients with CIDP are presented. It has been shown that the use of thioctic acid against the background of basic therapy for the treatment of CIDP is accompanied by a decrease in the severity and slowing the progression of sensory disorders that allows to recommend the use of drug in routine clinical practice.

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References

  1. Köller H., Kieseier B.C., Jander S., et al. Chronic inflammatory demyelinating polyneuropathy. N. Engl. J. Med. 2005;352:1343-56
  2. Panaite P.A., Renaud S., Kraftsik R., et al. Impairment and disability in 20 CIDP patients according to disease activity status. J. Peripher. Nerv. Syst. 2013;18(3):241-46
  3. Viala K., Maisonobe T., Stojkovic T., et al. A current view of the diagnosis, clinical variants, response to treatment and prognosis of chronic inflammatory demyelinating polyradiculoneuropathy. J. Peripher. Nerv. Syst. 2010;15(1):50-6.
  4. Хабиров Ф.А., Есин Р.Г., Хайбуллин Т.И. и др. Сенсорные расстройства при рассеянном склерозе и возможности их коррекции тиоктовой кислотой. Неврологический вестник. 2010;43(Вып. 1): 37-40.
  5. Stewart J.D., McKelvey R., Durcan L., et al. Chronic inflammatory demyelinating polyneuropathy (CIDP) in diabetics. J. Neurol. Sci. 1996;142:59-64.
  6. Schoene W.C., Carpenter S., Behan P.O., et al. «Onion bulb» formations in the central and peripheral nervous system in association with multiple sclerosis and hypertrophic polyneuropathy. Brain. 1977;100:755-73.
  7. Pineda A.A., Ogata K., Osoegawa M., et al. A distinct subgroup of chronic inflammatory demyelinating polyneuropathy with CNS demyelination and a favorable response to immunotherapy. J. Neurol. Sci. 2007: 225:1-6.
  8. Van den Bergh P.Y.K., Hadden R.D.M., Bouche P., et al. EFNS/PNS Guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint task force of the EFNS and the PNS - First Revision. Eur. J. Neurol. 2010;17:356-63.
  9. Тарасова Л.А., Лагутина Г.Н., Шардакова Э.Ф. и др. Методика исследования вибрационной чувствительности человека для рук вибротестером ВТ-02-1 «Вибротестер-МБН». Методические рекомендации. М., 2004. 14 с.

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