Primenenie kombinirovannoy terapii glimepiridom i metforminom u patsientov s sakharnym diabetom 2 tipa. Rezul'taty Rossiyskogo observatsionnogo issledovaniya


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Abstract

Lifestyle modification, which is the first step in the treatment of type 2 diabetes mellitus, even in case of simultaneous beginning of therapy with metformin, often does not lead to the achievement of carbohydrate metabolism control. Glimepiride, a representative of the third generation sulfonylureas, is one of the drugs of choice for the enhancement of antihyperglicemic therapy. The article presents the results of open multicenter observational study on the efficacy and safety of combined use of metformin and glimepiride, allows to significantly improve the status of carbohydrate metabolism in patients with type 2 diabetes mellitus. This therapy is safe due to the low risk of hypoglycaemia, lack of side effects and adverse effects on body weight.

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References

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