O protivoopukholevom effekte preparatov vitamina D3: fundamental'nye issledovaniya i dokazatel'naya meditsina


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Vitamin D is hormone involved in maintaining antitumor immunity. The article presents a comprehensive molecular and physiological model of antitumor effects of vitamin D. The data of evidence-based medicine, showing that long-term intake of vitamin D3 at doses of 800-1000 IU/day significantly reduces the risk of breast cancer, rectal cancer, and mortality from other forms of cancer, are discussed.

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  1. Saez M.E., Ramirez-Lorca R., Moron F.J., Ruiz A. The therapeutic potential of the calpain family: new aspects. Drug Discov. Today. 2006; 11(19-20): 917-23.
  2. Garland C.F., Garland F.C. Do sunlight and vitamin D reduce the likelihood of colon cancer? Int. J. Epidemiol. 1980; 9(3): 22 7-31.
  3. Ingraham B.A., Bragdon B., Nohe A. Molecular basis of the potential of vitamin D to prevent cancer. Curr. Med. Res. Opin. 2008; 24(1): 139-49.
  4. Никитинская О.А., Торопцова Н.В. Кальций и витамин D: анализ возможных положительных и отрицательных побочных явлений при их применении. РМЖ. 2011; 10: 651-55.
  5. Westerdahl J., Ingvar C., Masback A., et al. Risk of cutaneous malignant melanoma in relation to use of sunbeds: further evidence for UV-A carcinogenicity. Br. J. Cancer. 2000; 82(9): 1593-99.
  6. Torshin I.Yu. Sensing the change from molecular genetics to personalized medicine. In «Bioinformatics in the Post-Genomic Era» series. Nova Biomedical Books, NY, USA, 2009.
  7. Nagpal S., Songqing N., Radhakrishnan R. Noncalcemic Actions of Vitamin D Receptor Ligands Full Text Endocrine Reviews. 2005; 5: 662-87.
  8. Yee Y.K., Chintalacharuvu S.R., Lu J., Nagpal S. Vitamin D receptor modulators for inflammation and cancer. Mini Rev. Med. Chem. 2005; 5(8): 761-78.
  9. Martin S. New agents in clinical oncology. Drugs. 2007; 10( 2): 99-101.
  10. Gilad L.A., Bresler T. Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK1 /2 signaling pathway in colon and breast cancer cells. J. Endocrinol. 2005; 185(3): 577-92.
  11. Gilad L.A., Schwartz B. Association of estrogen receptor beta with plasma-membrane caveola components: implication in control of vitamin D receptor. J. Mol. Endocrinol. 2007; 38(6): 603.
  12. Abbas S., Linseisen J., Slanger T. Serum 25-hydroxyvitamin D and risk of postmenopausal breast cancer--results of a large case-control study. Carcinogenesis. 2008; 29(1): 93-9.
  13. Ding E.L., Mehta S., Fawzi W.W., Giovannucci E.L. Interaction of estrogen therapy with calcium and vitamin D supplementation on colorectal cancer risk: reanalysis of Women's Health Initiative randomized trial. Int. J. Cancer. 2008; 122(8): 1690-94.
  14. Lappe J.M., Travers-Gustafson D., Davies K.M. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am. J. Clin. Nutr. 2007; 85(6): 1586-91.
  15. Torshin I.Yu. Bioinformatics in the post-genomic era: physiology and medicine. Nova Biomedical Books, NY, USA 2007: 35-67.
  16. Tuohimaa P. Does solar exposure, as indicated by the non-melanoma skin cancers, protect from solid cancers: vitamin D as a possible explanation. Eur. J. Cancer. 2007; 43(11): 1701-12.
  17. Li H., Stampfer M.J., Hollis J.B. A prospective study of plasma vitamin D metabolites, vitamin D receptor polymorphisms, and prostate cancer. PLoS Med. 2007; 4(3): e103.
  18. Porojnicu A.C., Robsahm T.E. Seasonal and geographical variations in lung cancer prognosis in Norway. Does Vitamin D from the sun play a role? Lung Cancer. 2007; 55(3): 263-70.
  19. Garland C.F., Gorham E.D., Mohr S.B., et al. Vitamin D and prevention of breast cancer: pooled analysis. J. Steroid Biochem. Mol. Biol. 2007; 103(3-5): 708-11.
  20. John E.M., Schwartz G.G., Koo J., et al. Sun exposure, vitamin D receptor gene polymorphisms, and risk of advanced prostate cancer. Cancer Res. 2005; 65(12): 5470-79.
  21. Knight J.A., Lesosky M., Barnett H., et al. Vitamin D and reduced risk of breast cancer: a population-based case-control study. Cancer Epidemiol. Biomarkers Prev. 2007; 16(3): 422-29.
  22. Abbas S., Linseisen J. Dietary vitamin D and calcium intake and premenopausal breast cancer risk in a German case-control study. Nutr. Cancer. 2007; 59(1): 54-61.
  23. Hartman T.J., Albert P.S., Snyder K., et al. The association of calcium and vitamin D with risk of colorectal adenomas. J. Nutr. 2005; 135(2): 252-59.
  24. Senesse P., Touvier M., Kesse E. Tobacco use and associations of beta-carotene and vitamin intakes with colorectal adenoma risk. J. Nutr. 2005; 135( 10): 2468-72.
  25. ИНВИТРО, http: //www.invitro.ru/analizes/for-doctors/487/2849/?sphrase_id=8963164 (обращение на сайт 27.07.2014).
  26. Ng K., Meyerhardt J.A., Wu K., Feskanich D. Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer. J. Clin. Oncol. 2008; 26( 18): 2984-91.
  27. Wu K., Feskanich D., Fuchs C.S., et al. A nested case control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer. J. Natl. Cancer Inst. 2007; 99(14): 1120-29.
  28. Gorham E.D., Garland C.F., Garland F.C., et al. Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis. Am. J. Prev. Med. 2007; 32(3): 210-16.
  29. Peters U., Hayes R.B. Circulating vitamin D metabolites, polymorphism in vitamin D receptor, and colorectal adenoma risk. Cancer Epidemiol. Biomarkers Prev. 2004; 13(4): 546-52.
  30. Martinez M.E., Marshall J.R., Sampliner R., Wilkinson J., Alberts D.S. Calcium, vitamin D, and risk of adenoma recurrence (United States). Cancer Causes Control. 2002; 13(3): 213-20.
  31. Peters U., McGlynn K.A. Vitamin D, calcium, and vitamin D receptor polymorphism in colorectal adenomas. Cancer Epidemiol. Biomarkers Prev. 2001; 10(12): 1267-74.
  32. Abbas S., Linseisen J., Slanger T.J. The Gc2 allele of the vitamin D binding protein is associated with a decreased postmenopausal breast cancer risk, independent of the vitamin D status. Cancer Epidemiol. Biomarkers Prev. 2008; 17(6): 1339-43.
  33. Trabert B., Malone K.E., Daling J.R., et al. Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women. Breast Cancer Res. 2007; 9(6): R84.
  34. Li C., Liu Z., Zhang Z., et al. Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma. J. Invest. Dermatol. 2007; 127(2): 276-80.
  35. Sillanpaa P., Hirvonen A., Kataja V. Vitamin D receptor gene polymorphism as an important modifier of positive family history related breast cancer risk. Pharmacogenetics. 2004; 14(4): 239-45.
  36. Zhang K., Song L. Association between vitamin D receptor gene polymorphisms and breast cancer risk: a meta-analysis of 39 studies. PLoS One. 2014; 9(4): e96125.
  37. Ahn J., Yu K., Stolzenberg-Solomon R., et al. Serum 25-hydroxyvitamin D and breast cancer risk: a meta-analysis of prospective studies. Tumour Biol. 2013; 34(6): 3509-17.
  38. Wang D., Velez de-la-Paz O.I., Zhai J.X., Liu D.W. Serum 25-hydroxyvitamin D and breast cancer risk: a meta-analysis of prospective studies. Tumour Biol. 2013; 34(6): 3509-17.
  39. Bauer S.R., Hankinson S.E., Bertone-Johnson E.R., Ding E.L. Plasma vitamin D levels, menopause, and risk of breast cancer: dose-response meta-analysis of prospective studies. Medicine. (Baltimore) 2013; 92(3): 123-31.
  40. Chen P., Li M., Gu X., et al. Higher blood 25(OH)D level may reduce the breast cancer risk: evidence from a Chinese population based case-control study and meta-analysis of the observational studies. PLoS One. 2013; 8(1): e49312.
  41. Hong Z., Tian C., Zhang X. Dietary calcium intake, vitamin D levels, and breast cancer risk: a dose-response analysis of observational studies. Breast Cancer Res. Treat. 2012; 1 36(1): 309-12.
  42. Mohr S.B., Gorham E.D., Alcaraz J.E., et al. Serum 25-hydroxyvitamin D and prevention of breast cancer: pooled analysis. Anticancer Res. 2011; 31(9): 2939-48.
  43. Chen P., Hu P., Xie D., et al. Meta-analysis of vitamin D, calcium and the prevention of breast cancer. Breast Cancer Res. Treat. 2010; 121(2): 469-77.
  44. Chung M., Lee J., Terasawa T., et al. Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the U.S. Preventive Services Task Force. Ann. Intern. Med. 2011; 155(12): 827-38.
  45. Yin L., Grandi N., Raum E., et al. Meta-analysis: Serum vitamin D and colorectal adenoma risk. Prev. Med. 2011; 53(1-2): 10-6.
  46. Lee J.E., Li H., Chan A.T., et al. Circulating levels of vitamin D and colon and rectal cancer: the Physicians' Health Study and a meta-analysis of prospective studies. Cancer Prev. Res. (Phila). 2011; 4(5): 735-43.
  47. Touvier M., Chan D.S., Lau R., Aune D. Metaanalyses of vitamin D intake, 25-hydroxyvitamin D status, vitamin D receptor polymorphisms, and colorectal cancer risk. Cancer Epidemiol. Biomarkers Prev. 2011; 20(5): 1003-16.
  48. Lagunova Z., Porojnicu A.C. Obesity and increased risk of cancer: does decrease of serum 25-hydroxyvitamin D level with increasing body mass index explain some of the association? Mol. Nutr. Food Res. 2010; 54(8): 1127-33.
  49. Schottker B., Jorde R., Peasey A., et al. Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States. BMJ. 2014; 348: g3656.
  50. Keum N., Giovannucci E. Vitamin D supplements and cancer incidence and mortality: a meta-analysis. Br. J. Cancer. 2014; 101038/bjc2014294.
  51. Yin L., Ordonez-Mena J.M., Chen T., et al. Circulating 25-hydroxyvitamin D serum concentration and total cancer incidence and mortality: a systematic review and meta-analysis. Prev. Med. 2013; 57(6): 753-64.
  52. Zheng Y., Zhu J., Zhou M., et al. Meta-analysis of long-term vitamin D supplementation on overall mortality. PLoS One. 2013; 8(12): e8210.
  53. Kim Y., Je Y. Vitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a meta-analysis. Br. J. Cancer. 2014; 110(11): 2772-84.
  54. Громова О.А., Торшин И.Ю., Лиманова О.А., Громов А.Н., Керимкулова Н.В. Сравнительное исследование доказательной базы эффективности и безопасности применения пероральной и трансдермальной форм заместительной гормональной терапии эстрогенами у женщин в различные возрастные периоды. Проблемы репродукции. 2013; 6: 86-96.

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