Klinicheskaya inertsiya v terapii sakharnogo diabeta 2 tipa


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Abstract

The article justifies the necessity of intensification of therapy to improve glycemic control in patients with type 2 diabetes mellitus (DM2) and reduce the risk of diabetic complications. Unfortunately, clinical inertia, or the tendency to follow the selected course of treatment independent of the outcome requiring intensification of therapy, significantly reduces the effectiveness of therapy in patients with DM2. The potentials for overcoming of clinical inertia by using dipeptidyl peptidase-4 inhibitor vildagliptin are considered. This is because this drug, along with high hypoglycemic activity, has a low risk of hypoglycemia with the possibility of using in moderate renal and liver impairments, and is well tolerated. Overcoming of multifactorial nature of clinical inertia requires efforts from both physicians and patients. The emergence of effective and safe drugs for the treatment of DM2 may have a positive effect on the willingness of patients to follow medical recommendations, thus solving this problem.

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M. B Antsiferov

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