Effektivnost' i bezopasnost' vtorichnoy profilaktiki ishemicheskogo insul'ta antitrombotsitarnymi preparatami i peroral'nymi antikoagulyantami


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Abstract

Ischemic stroke (IS) is a common serious disease characterized by high mortality and permanent disability. Cardioembolism is one of the common pathogenetic subtypes of IS. The most effective way to prevent the development of this subtype of IS includes the use of indirect anticoagulants, such as warfarin. Its effectiveness has been repeatedly confirmed by clinical studies. The drug is characterized by reliable anticoagulant effect with acceptable cost to most patients. The apparent advantage of warfarin is the ability to laboratory control of anticoagulant effect. It is important to emphasize the absence of the drug nephrotoxicity and hepatotoxicity. The application of warfarin for the prevention of IS is discussed.

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