Struktura slizistoy obolochki zheludka u bol'nykh rakom zheludka v Respublike Khakasiya


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Abstract

Morphological examinations of the gastric mucosa with Helicobacter pylori infection testing were performed in 127 Caucasians and 132 Khakases with gastritis and in 51 newcomers and 32 Mongoloids with stomach cancer. In both populations, the incidence of atrophy and metaplasia in the gastric antrum and body was significantly higher in patients with gastric cancer compared with those with gastritis. The ethnic differences in the incidence of metaplasia between native and immigrant population with stomach cancer were determined. In Caucasians and Mongoloids H. pylori was detected more frequently in patients with distal cancer, compared to the proximal localization of the tumor. It is stressed that the concept of the Correa 's cascade of gastric carcinogenesis rationally describes the study results which confirm the feasibility of putting into practice the modern consensus on this clinical problem.

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