OSTEOPOROZ I ATEROSKLEROZ: ChTO OBShchEGO?


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Abstract

This review article discusses some of the issues about the linkages between osteoporosis and cardiovascular diseases, common pathogenetic mechanisms and therapeutic options.

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References

  1. Danilevicius C.F., Lopes J.B., Pereira R.M.R. Bone metabolism and vascular calcification. Brazilian Journal of Medical and Biological Research. 2007; 40(4): 435-42.
  2. Farhat G.N., Newman A.B., Sutton-Tyrrell K., Matthews K.A., Boudreau R., Schwartz A.V., Harris T., Tylavsky F., Visser M., Cauley J.A.; Health ABC Study. The association of bone mineral density measures with incident cardiovascular disease in older adults. Osteoporos. Int. 2007; 18(7): 999-1008.
  3. Perez Castrillon J.L., de Luis D., Duenas-Laita A. Atherosclerosis and osteoporosis. Minerva Med. 2008; 99(1): 45-54.
  4. Коков А.Н., Малюта Е.Б., Масенко В.Л., Сигарева А.А., Фанасков В.Б., Тарасов Р.С., Раскина Т.А., Шибанова И.А., Барбараш О.Л. Оценка поражения коронарных артерий у мужчин с остеопеническим синдромом и ишемической болезнью сердца. Терапевтический архив. 2014; 86(3): 65-70.
  5. Divers J., Register T.C., Langefeld C.D., Wagenknecht L.E., Bowden D.W., Carr J.J., Hightower R.C., Xu J., Hruska K.A., Freedman B.I. Relationships between calcified atherosclerotic plaque and bone mineral density in African Americans with type 2 diabetes. J. Bone Miner. Res. 2011;26(7):1554-60.
  6. Anagnostis P., Karagiannis A., Kakafika A.I., Tziomalos K., Athyros V.G., Mikhailidis D.P. Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities? Osteoporos Int. 2009;20(2):197-207.
  7. Schulz E., Arfai K., Liu X., Sayre J., Gilsanz V. Aortic calcification and the risk of osteoporosis and fractures. J. Clin. Endocrinol. Metab. 2004; 89(9): 4246-53.
  8. Osako M.K., Nakagami H., Koibuchi N.,Shimizu H., Nakagami F., Koriyama H., Shimamura M., Miyake T., Rakugi H., Morishita R. Estrogen inhibits vascular calcification via vascular RANKL system: common mechanism of osteoporosis and vascular calcification. Circ. Res. 2010; 107(4): 466-75.
  9. Baldini V., Mastropasqua M., Francucci C.M., D'Erasmo E. Cardiovascular disease and osteoporosis. J. Endocrinol. Invest. 2005; 28: 69-72.
  10. Askim M. Vitamin K in the Norwegian diet and osteoporosis. Tidsskrift for den Norske læge-forening: tidsskrift for praktisk medicin, ny række. Tidsskr Nor Laegeforen. 2001; 121: 2614-16.
  11. Iwamoto J., Takeda T., Sato Y. Role of vitamin K2 in the treatment of postmenopausal osteoporosis. Current drug safety. 2006; 1: 87-97.
  12. Vermeer C., Shearer M.J., Zittermann A. Beyond deficiency potential benefits of increased intakes of vitamin K for bone and vascular health. Eur. J. Nutr. 2004; 43: 325-35.
  13. Schurgers L.J., Dissel P.E., Spronk H.M. Role of vitamin K and vitamin K dependent proteins in vascular calcification. Zeitschrift für Kardiologie. 2001; 90(3): 57-63.
  14. Abedin M., Omland T., Ueland T., Khera A., Aukrust P., Murphy S.A., Jain T., Gruntmanis U., McGuire D.K., de Lemos J.A. Relation of osteoprotegerin to coronary calcium and aortic plaque (from the Dallas Heart Study). Am. J. Cardiol. 2007; 99(4): 513-8.
  15. Lieb W., Gona P., Larson M.G., Massaro J.M., Lipinska I., Keaney J.F. Jr., Rong J., Corey D., Hoffmann U., Fox C.S., Vasan R.S., Benjamin E.J., O'Donnell C.J., Kathiresan S. Biomarkers of the osteoprotegerin pathway: clinical correlates, subclinical disease, incident cardiovascular disease, and mortality. Arterioscler. Thromb. Vasc. Biol. 2010; 30(9): 1849-54.
  16. Kiechl S., Schett G., Wenning G., Redlich K., Oberhollenzer M., Mayr A., Santer P., Smolen J., Poewe W., Willeit J. Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease. Circulation. 2004; 109(18): 2175-80.
  17. Anand D.V., Lahiri A., Lim E., Hopkins D., Corder R. The relationship between plasma osteoprote-gerin levels and coronary artery calcification in uncomplicated type 2 diabetic subjects. J. Am. Coll. Cardiol. 2006; 47(9): 1850-57.
  18. Shin J.Y., Shin Y.G., Chung C.H. Elevated serum osteoprotegerin levels are associated with vascular endothelial dysfunction in type 2 diabetes. Diabetes Care. 2006; 29: 1664-6.
  19. Morena M., Terrier N., Jaussent I., Leray-Moragues H., Chalabi L., Rivory J.P., Maurice F., Delcourt C., Cristol J.P., Canaud B., Dupuy A.M. Plasma osteoprotegerin is associated with mortality in hemodialysis patients. J. Am. Soc. Nephrol. 2006; 17(1): 262-70.
  20. Roysland R., Bona ca M.P., Omla nd T., Saba tine M., Murphy S.A., Scirica B.M., Bjerre M., Flyvbjerg A., Braunwald E., Morrow D.A. Osteoprotegerin and cardiovascular mortality in patients with non-ST elevation acute coronary syndromes. Heart. 2012; 98(10): 786-91.
  21. Ueland T., Yndestad A., Oie E., Florholmen G., Halvorsen B., Frland S.S., Simonsen S., Christensen G., Gullestad L., Aukrust P. Dysregulated osteoprotegerin / RANK ligand / RANK axis in clinical and experimental heart failure. Circulation. 2005; 111(19): 2461-8.
  22. van Diepen S., Majumdar S.R., Bakal J.A., McAlister F.A., Ezekowitz J.A. Heart failure is a risk factor for orthopedic fracture: a population-based analysis of 16,294 patients. Circulation. 2008; 118: 1946-52.
  23. Loncar G., Bozic B., Cvorovic V., Radojicic Z., Dimkovic S., Markovic N., Prodanovic N., Lepic T., Putnikovic B., Popovic-Brkic V. Relationship between RANKL and neuroendocrine activation in elderly males with heart failure. Endocrine. 2010; 37(1): 148-56.
  24. Carbone L., Buzkova P., Fink H.A., Lee J.S., Chen Z., Ahmed A., Parashar S., Robbins J.R. Hip fractures and heart failure: findings from the Cardiovascular Health Study. Eur. Heart. J. 2010; 31(1): 77-84.
  25. Loncar G., Fulster S., von Haehling S., Popovic V. Metabolism and the heart: an overview of muscle, fat, and bone metabolism in heart failure. Int. J. Cardiol. 2013; 162(2): 77-85.
  26. Andersen G.O., Knudsen E.C., Aukrust P., Yndestad A., Oie E., Müller C., Seljeflot l., Ueland T. Elevated serum osteoprotegerin levels measured early after acute ST-elevation myocardial infarction predict final infarct size. Heart. 2011; 97(6): 460-65.
  27. Cummings S.R., San Martin J., McClung M.R., Siris E.S., Eastell R., Reid I.R., Delmas P., Zoog H.B., Austin M., Wang A., Kutilek S., Adami S., Zanchetta J., Libanati C., Siddhanti S., Christiansen C.; FREEDOM Trial. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N. Engl. J. Med. 2009; 361(8): 756-65.
  28. Collin-Osbody P. Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin. Circ. Res. 2004; 95(11): 1046-57.
  29. Panizo S., Cardus A., Encinas M., Parisi E., Valcheva P., Lopez-Ongil S., Coll B., Fernandez E., Valdivielso J.M. RANKL increases vascular smooth muscle cell calcification through a RANKL-BMP4- dependent pathway. Circ. Res. 2009; 104(9): 1041-48.
  30. Chen S., Law C.S., Grigsby C.L., Olsen K., Hong T.T., Zhang Y., Yeghiazarians Y., Gardner D.G. Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy. Circulation. 2011; 124: 1838-47.
  31. Seibert E., Levin N.W., Kuhlmann M.K. Immunomodulating effects of vitamin D analogs in hemodialysis patients. Hemodial. Int. 2005; 9(s4): S25-S29.
  32. Holick M.F. Vitamin D deficiency. N. Engl. J. Med. 2007; 357(3): 266-81.
  33. Bischoff-Ferrari H.A., Giovannucci E., Willett W.C., Dietrich T., Dawson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health out comes. Am. J. Clin. Nutr. 2006; 84(1): 18-28.
  34. Poole K.E., Loveridge N., Barker P.J., Halsall D.J., Rose C., Reeve J., Warburton E.A. Reduced vitamin D in acute stroke. Stroke. 2006; 37(1): 243-45.
  35. Zittermann A. Vitamin D and disease prevention with special reference to cardiovascular disease. Progress in Biophysics and Molecular Biology. 2006; 92(1): 39-48.
  36. Melamed M.L., Muntner P., Michos E.D., Uribarri J., Weber C., Sharma J., Raggi P. Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004. Arterioscler. Thromb. Vasc. Biol. 2008; 28(6): 1179-85.
  37. Martins D., Wolf M., Pan D., Zadshir A., Tareen N., Thadhani R., Felsenfeld A., Levine B., Mehrotra R., Norris K. Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. Arch. Intern. Med. 2007; 167(11): 1159-65.
  38. Вербовой А.Ф., Шаронова Л.А., Капишников А.В., Демидова Д.В. Витамин D3, остеопротегерин и другие гормональнометаболические показатели у мужчин с сахарным диабетом 2 типа. Терапевт. 2013; 1: 42-8.
  39. Zipitis C.S., Akobeng A.K. Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis. Arch. Dis. Child. 2008; 93: 512-17.
  40. Riachy R., Vandewalle B., Moerman E., Belaich S., Lukowiak B., Gmyr V., Muharram G., Kerr Conte J., Pattou F. 1,25-Dihydroxyvitamin D3 protects human pancreatic islets against cytokine-induced apoptosis via down-regulation of the Fas receptor. Apoptosis. 2006; 11(2): 151-59.
  41. Wang T.J., Pencina M.J., Booth S.L., Lages J.S., Filho N.S. Vitamin D deficiency and risk of cardiovascular disease. Circulation. 2008; 117(4): 503-11.
  42. Zittermann A., Schleithoff S.S., Koerfer R. Vitamin D and vascular calcification. Current Opinion in Lipidology. 2007; 18(1): 41-6.
  43. Sloka S., Silva C., Wang J., Yong V.W. Predominance of Th2 polarization by vitamin D through a STAT6-dependent mechanism. J. Neuroinflammation. 2011; 8: 56.
  44. Sambrook P.N., Chen C.J., March L., Cameron I.D., Cumming R.G., Lord S.R., Simpson J.M., Seibel M.J. High bone turnover is an independent predictor of mortality in the frail elderly. J. Bone Miner Res. 2006; 21(4): 549-55.
  45. Oh J., Weng S., Felton S.K., Bhandare S., Bhandare S., Riek A., Butler B., Proctor B.M., Petty M., Chen Z., Schechtman K.B., Bernal-Mizrachi L., Bernal-Mizrachi C. 1,25(OH)2 vitamin D inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus. Circulation. 2009; 120(8): 687-98.
  46. Schleithoff S.S., Zittermann A., Tenderich G., Berthold H.K., Stehle P., Koerfer R. Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a doubleblind, randomized, placebo-controlled trial. Am. J. Clin. Nutr. 2006; 83(4): 754-59.
  47. Hsia J., Heiss G., Ren H., Allison M., Dolan N.C., Greenland P., Heckbert S.R., Johnson K.C., Manson J.E., Sidney S., Trevisan M.; Women's Health Initiative Investigators. Calcium / vitamin D supplementation and cardiovascular events. Circulation. 2007; 115(7): 846-54.
  48. Bischoff-Ferrari H.A., Dawson-Hughes B., Baron J.A., Burckhardt P., Li R., Spiegelman D., Specker B., Orav J.E., Wong J.B., Staehelin H.B., O'Reilly E., Kiel D.P., Willett W.C. Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials. Am. J. Clin. Nutr. 2007; 86(6): 1780-90.
  49. Bolland M.J., Avenell A., Baron J.A., Grey A., MacLennan G.S., Gamble G.D., Reid I.R. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ. 2010; 341: 3691.
  50. Dietary Reference Intakes for Calcium and Vitamin D. Institute of Medicine. Washington, D.C.: The National Academies Press, 2010.
  51. Melamed M.L., Michos E.D., Post W., Astor B. 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch. Intern. Med. 2008; 168(15): 1629-37.
  52. Zheng Y., Zhu J., Zhou M., Cui L., Yao W., Liu Y. Meta-analysis of long-term vitamin D supplementation on overall mortality. PLoS ONE. 2013; 8(12): e82109.
  53. Bjelakovic G., Gluud L.L., Nikolova D., Whitfield K., Wetterslev J., Simonetti R.G., Bjelakovic M., Gluud C. Vitamin D supplementation for prevention of mortality in adults. Cochrane Database Syst. Rev. 2014; 1: CD007470.

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