INCREASED THYROID-STIMULATING HORMONE LEVEL AS A MARKER OF PROGRESSION OF HEART FAILURE IN CARDIAC PATIENTS


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Abstract

The study including 42 patients has investigated the relationship of subclinical hypothyroidism (SH) with the development and progression of heart failure in patients with coronary heart disease and hypertension. It was found that SH (increased thyroid-stimulating hormone level) is accompanied by maladaptive restructuring of the left ventricle and its dilation, which is a prerequisite for an earlier development and progression of chronic heart failure in cardiac patients. These data suggest the presence of the negative impact of the SH on the dilation of the left atrium and development of atrial fibrillation, which requires a large-scale studies on the subject. They also put on the agenda the question of whether screening for thyroid disorders in cardiac patients and earlier initiation of hormone replacement therapy for the SH will reduce the risk and progression of heart failure.

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About the authors

A. S Adamchik

SBEI HPE “Kuban State Medical University" of RMPH MD, Prof., Head of the Department of Propaedeutics of Internal Diseases Krasnodar

D. I Panchenko

SBEI HPE “Kuban State Medical University" of RMPH Krasnodar

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