MODERN PRINCIPLES OF PROPHYLACTIC THERAPY OF MIGRAINE IN CHILDREN AND ADOLESCENTS


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Abstract

Migraine in children and adolescents affects the quality of life not only the child, but the family as a whole. The choice of treatment tactics must rely on the age, characteristics of the disease, comorbidities, the patient's individual characteristics, and combine both drugs and non-drug therapies. Preventive migraine therapy is aimed at improvement of patient’s condition, and allows avoiding or reducing the progression of the disease in adulthood. At present, such drugs as amitriptyline, topiramate, valproic acid have sufficient evidence base of effectiveness of prophylactic therapy. Nutraceuticals are alternative prophylactic treatment of migraine in children and can be offered in cases when the parents do not agree to accept traditional medicines. There are publications about the effectiveness of coenzyme Q10 and riboflavin in the prophylactic treatment of migraine in children. Also, the effectiveness of drug therapy in children is increased by the additional use of non-drug methods of treatment.

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About the authors

Yu. E Nesterov

SBEIHPE RNSMU n.a. N.I. Pirogov of RMPH

Department of Neurology, Neurosurgery and Medical Genetics Moscow

N. N Zavadenko

SBEI HPE RNSMU n.a. N.I. Pirogov of RMPH

Email: zavadenko@mail.ru
MD, Prof., Head of the Department of Neurology, Neurosurgery and Medical Genetics Moscow

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