Molekulyarnye funktsii magniy-zavisimykh belkov miokarda ukazyvayut na perspektivy kardiologicheskogo primeneniya preparatov na osnove orotata magniya


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Abstract

The article presents modern data on the regulatory effect of magnesium on the cardiovascular system. Cardioprotective effects of magnesium are substantiated. Significance of magnesium-dependent proteins, supporting the function of the myocardium, is considered. The best ways to correct magnesium deficiency, particularly in cardiac patients, are discuss. The use of second generation magnesium preparations, containing organic magnesium salts with high bioavailability, is most promising. Magnesium orotate - is one of such drugs. The efficiency of magnesium orotate in conditions with magnesium deficiency, especially in patients undergoing coronary surgery, is demonstrated. The drug has antiarrhythmic, vasodilating and cardioprotective effects. Increasing myocytes resistance to ischemia, magnesium orotate has positive effect on the clinical course of myocardial infarction and heart failure. Orotate magnesium is also effective in idiopathic mitral valve prolapse

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About the authors

I. Yu Torshin

FSAEI HPE "Moscow Institute of Physics and Technology"

Dolgoprudny

O. A Gromova

SBEI HPE "Ivanovo State Medical Academy" of RMPH

Email: unesco.gromova@gmail.com
MD, Prof. at the Department of Pharmacology and Clinical Pharmacology Ivanovo

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