Современные возможности профилактики и лечения желчнокаменной болезни в период беременности


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Аннотация

В статье представлены современные литературные данные по эпидемиологии, патогенезу и современным подходам к лечению желчнокаменной болезни (ЖКБ) и билиарного сладжа (БС) в период беременности. Приведены результаты собственных наблюдений, позволившие выделить факторы риска ЖКБ у беременных. Несмотря на транзиторный характер БС/ЖКБ и их спонтанный регресс после родов у части пациенток, следует учитывать и те случаи, когда конкременты и микролиты в желчевыводящих путях сохраняются и являются причиной осложнений, требующих в дальнейшем хирургического лечения. Продемонстрирована эффективность и безопасность применения препаратов урсодезоксихолевой кислоты в комбинации с холекинетиками/холеретиками для лечения и профилактики БС у беременных. Целесообразен динамический контроль за состоянием желчного пузыря во время беременности и в послеродовом периоде при наличии БС, особенно в группах риска, и при необходимости - проведение более длительных и/или повторных курсов лечения.

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Ю. Б Успенская

ГБОУ ВПО «Первый МГМУ им. И.М. Сеченова» Минздрава России

Email: Moscow; e-mal: jusp@mail.ru
к.м.н., в.н.с. научно-исследовательского отдела женского здоровья НИЦ

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