ANTIBACTERIAL THERAPY PROVOKES DEVELOPMENT OF MAGNESIUM DEFICIENCY. WHAT IS TO BE DONE?


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Аннотация

There are antagonistic interactions between magnesium (Mg) and certain antibiotics (especially aminoglycosides and fluoroquinolones). First, the antibacterial therapy causes rapid loss of Mg, necessitating the appointment of magnesium preparations. Secondly, the simultaneous use of magnesium preparations and fluoroquinolone or aminoglycosides leads to complex formation, which reduces the effectiveness of antibiotics and disrupts the absorption of Mg. Third, Mg deficiency leads to a decrease in barrier function and as a result - to a decrease in the antibacterial and antiviral immunity. Therefore, separate use of antibiotics and Mg can increase the effectiveness and safety of antibacterial therapy.

Толық мәтін

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Авторлар туралы

O. Gromova

SBEI HPE «Ivanovo State Medical Academy»

MD, Prof. at the Department of Pharmacology and Clinical Pharmacology Ivanovo

I. Torshin

FSAEI HPE «Moscow Institute of Physics and Technology (State University),»

Moscow

O. Limanova

SBEI HPE «Ivanovo State Medical Academy»

Ivanovo

L. Fedotova

SBEI HPE «Ivanovo State Medical Academy»

Ivanovo

A. Kalacheva

SBEI HPE «Ivanovo State Medical Academy»

Ivanovo

T. Grishina

SBEI HPE «Ivanovo State Medical Academy»

Ivanovo

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