FIRST-LINE ENDOCRINE THERAPY OF HORMONE RECEPTOR-POSITIVE HER2-NEGATIVE METASTATIC BREAST CANCER. TIME OF CHANGE AFTER A LONG-TERM CALM PERIOD


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Abstract

Over the past year we have seen a change in principles of endocrine therapy of hormone receptor-positive breast cancer in general, and the first-line therapy in particular. The article presents the results of Phase III FALCON trial reported in Copenhagen during ESMO Congress. This trial has confirmed the benefit of fulvestrant as first-line endocrine therapy in relation to progression-free survival compared to the use of an aromatase inhibitor - anastrozole, standard variant existing for a long time.

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L. G Zhukova

Email: zhukova.lyudmila@rambler.ru
FSBI RORC n.a. N.N. Blokhin of RMH MD, Leading Researcher at the Department of Chemotherapy and Combined Therapy of Malignant Tumors Moscow

A. G Manikhas

FSBI RORC n.a. N.N. Blokhin of RMH Moscow

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