TAXANES IN THE TREATMENT OF BREAST CANCER


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Abstract

The article considers the modern approaches to the use of taxanes (paclitaxel and docetaxel) in the therapy of breast cancer (BC). Numerous studies show that taxane-containing chemotherapy improves short- and long-term results of treatment at all BC stages, and in all biological subtypes of BC, except for early (operable) stages of luminal A-type BC. Prospects for application of the representative of a new generation taxane - nab-paclitaxel (Abraxan®), more efficient compared with standard paclitaxel, are discussed.

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About the authors

V. F Semiglazov

FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH St. Petersburg

G. A Dashyan

FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH St. Petersburg

V. V Semiglazov

St. Petersburg State Medical University n.a. Acad. I.P. Pavlov of RMH St. Petersburg

R. M Paltuev

FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH St. Petersburg

T. Yu Semiglazova

FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH St. Petersburg

R. V Donskikh

FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH St. Petersburg

K. S Nikolaev

Email: kirill.nikolaev87@gmail.com
FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH PhD, Researcher, Oncologist at the Surgical Department of Breast Tumors St. Petersburg

A. V Komyakhov

FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH St. Petersburg

K. Yu Zernov

FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH St. Petersburg

P. V Krivorotko

FSBI “SRI of Oncology n.a. N.N. Petrov" of RMH St. Petersburg

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